Olsenella profusa

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Olsenella profusa is a Gram-positive, non-spore-forming, microaerophilic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 64%. Olsenella profusa is probably a rare gut coloniser. (Dewhirst2001; Kraatz2011; Li2015)



  • This organism has been recovered from human faeces, and oral cavity. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • QUIRKS
  • Differences in enzyme activities between published reports are labelled 'vr' and might represent strain variability.
    • GENERAL CHARACTERISTICS (Dewhirst2001); (Kraatz2011); (Li2015);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; mucin;
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; glucose; mannose; rhamnose; xylose; cellubiose; lactose; maltose; melibiose; raffinose; sucrose; trehalose; glycerol; mannitol; sorbitol; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • mucin;
  • Active enzymes:
  • acid phosphatase; arginine dihydrolase; cystine arylamidase; α-glucosidase; G6PDH and 6PGDH; Leu arylamidase; Val arylamidase;
    • SPECIAL FEATURES (Kraatz2011); (Li2015);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate;
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • Nitrate:
  • not reduced

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Coriobacteriales Family:  Atopobiaceae Genus:  Olsenella Gram stain:  + O2 Relation.:  microaerophilic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, and oral cavity
    DNA G+C(%):  64
    		Aesculin:  + Urea:  neg Gelatin:  vr Starch:  neg Arginine:  neg Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  + Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  + Glycerol:  + Mannitol:  + Sorbitol:  + Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg G6PDH6PGDH:  + α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  vr β-Glucuronidase:  vr α-Mannosidase:  neg ArgDH:  + Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  vr ArgAA:  vr CystineAA:  + GluGluAA:  neg GlyAA:  r HisAA:  vr LeuAA:  + LeuGlyAA:  vr ProAA:  vr PyrrolidAA:  neg PheAA:  vr PyrogluAA:  neg SerAA:  vr TyrAA:  vr ValAA:  + AlkalineP:  vr AcidP:  + Esterase(C4):  neg EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Lactate:  + H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR OLSENELLA PROFUSA
  • Dewhirst2001 - Characterization of novel human oral isolates and cloned 16S rDNA sequences that fall in the family Coriobacteriaceae: description of olsenella gen. nov., reclassification of Lactobacillus uli as Olsenella uli comb. nov. and description of Olsenella profusa sp. nov.
  • Kraatz2011 - Olsenella umbonata sp. nov., a microaerotolerant anaerobic lactic acid bacterium from the sheep rumen and pig jejunum, and emended descriptions of Olsenella, Olsenella uli and Olsenella profusa.
  • Li2015 - Olsenella scatoligenes sp. nov., a 3-methylindole- (skatole) and 4-methylphenol- (p-cresol) producing bacterium isolated from pig faeces.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR OLSENELLA PROFUSA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • Added: April 08, 2021