Paenibacillus senegalensis

(aka Bacillus senegalensis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Paenibacillus senegalensis, (aka Bacillus senegalensis), is a Gram-negative, spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 48.2%. Paenibacillus senegalensis is probably a rare gut coloniser. (Mishra2012b; Guilhot2016; Senghor2017; Seck2015a)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Mishra2012b); (Senghor2017); (Seck2015a);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; D-tagatose; aesculin; inulin; lactose; maltose; sucrose; trehalose; sorbitol; arbutin; N-Ac glucosamine;
  • Active enzymes:
  • alkaline phosphatase; N-Ac β-glucosaminidase; α-galactosidase; α-glucosidase; β-glucuronidase; Leu arylamidase;
    • SPECIAL FEATURES (Mishra2012b); (Seck2015a);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Mishra2012b); (Seck2015a);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; imipenem;
  • Quinolines:
  • ciprofloxacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;
  • metronidazole;
  • Vancomycins:
  • vancomycin;

  • Pfleiderer, A., Lagier, J.-C., Armougom, F., Robert, C., Vialettes, B., & Raoult, D. (2013). Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample. European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology, 32(11), 1471–1481. Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Bacillales Family:  Paenibacillaceae Genus:  Paenibacillus Alt. name:  Bacillus senegalensis Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:   Positive
    Source:  human faeces
    DNA G+C(%):  48.2
    Opt. T:  37℃
    Lower T(℃):  30(+)
    High T(℃):  45(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  + Galactose:  + Glucose:  + Mannose:  + D-Tagatose:  + Lactose:  + Maltose:  + Sucrose:  + Trehalose:  + Aesculin:  + Inulin:  + Sorbitol:  + Arbutin:  + NAc-α-GA:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Ac-β-glcamnd:  + α-Galactosidase:  + α-Glucosidase:  + β-Glucuronidase:  + LeuAA:  + AlkalineP:  + AcidP:  w EstLip(C8):  w
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    imipenem:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens
    rifampicin:  Sens
    metronidazole:  Res
    SXT:  Sens

    References

    SPECIFIC REFERENCES FOR PAENIBACILLUS SENEGALENSIS
  • Mishra2012b - Non-contiguous finished genome sequence and description of Paenibacillus senegalensis sp. nov.
  • Guilhot2016 - Anaeromassilibacillus senegalensis gen. nov., sp. nov., isolated from the gut of a child with kwashiorkor.
  • Senghor2017 - Description of 'Bacillus dakarensis' sp. nov., 'Bacillus sinesaloumensis' sp. nov., 'Gracilibacillus timonensis' sp. nov., 'Halobacillus massiliensis' sp. nov., 'Lentibacillus massiliensis' sp. nov., 'Oceanobacillus senegalensis' sp. nov., 'Oceanobacillus timonensis' sp. nov., 'Virgibacillus dakarensis' sp. nov. and 'Virgibacillus marseillensis' sp. nov., nine halophilic new species isolated from human stool.
  • Seck2015a - Virgibacillus senegalensis sp. nov., a new moderately halophilic bacterium isolated from human gut.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PAENIBACILLUS SENEGALENSIS
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR PAENIBACILLUS SENEGALENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021