Parabacteroides johnsonii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Parabacteroides johnsonii is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 18 gut microbiome compilation studies or metastudies. The DNA G+C content is 45.2%. Parabacteroides johnsonii is a common gut coloniser. (Sakamoto2007a)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Sakamoto2007a);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; L-arabinose; glucose; mannose; xylose; lactose; sucrose;
  • ±
  • Strain-dependent acid from carbs:
  • rhamnose; maltose; raffinose; trehalose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; arabinosidase; N-Ac β-glucosaminidase; catalase; α-galactosidase; β-galactosidase; α-glucosidase; glutamic acid decarboxylase; Gly arylamidase; His arylamidase; Leu arylamidase; Leu-Gly arylamidase; Phe arylamidase; Ser arylamidase; Tyr arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • β-glucuronidase; Glu-Glu arylamidase;
    • SPECIAL FEATURES (Sakamoto2007a);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced

  • Bacteroides and Parabacteroides species are components of the colon resident microbiota, and both genera belong to the order Bacteroidales. Species of these genera are often associated with opportunistic mixed infections, such as intra-abdominal, obstetric-gynecologic and diabetic foot infections. In addition, these microorganisms are able to develop resistance to several antimicrobial drugs. Although antibiotics with good activity against these bacteria are currently available, high frequencies of resistance to some antimicrobials have been reported in several countries. Bacteroides and Parabacteroides species produce endogenous �_-lactamases, the most important mechanism of resistance to �_-lactam antibiotics. [PMID: 21655744]

  • GutFeeling KnowledgeBase COMMENTS [Website]

    Bacteroides and Parabacteroides species are components of the colon resident microbiota, and both genera belong to the order Bacteroidales. [PMID: 21655744] Cells are Gram-negative, obligately anaerobic, non-spore-forming, non-motile and rod-shaped, and 0.8-1.6μm in size. Major end-products are acetic and succinic acids. [PMID: 16825636]

  • Sakamoto, M., Kitahara, M., & Benno, Y. (2007). Parabacteroides johnsonii sp. nov., isolated from human faeces. International Journal of Systematic and Evolutionary Microbiology, 57(Pt 2), 293–296.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Tannerellaceae Genus:  Parabacteroides Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  45.2
    Bile reaction(%):  20(+)
    		Aesculin:  + Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + L-Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  d Xylose:  + Cellubiose:  neg Lactose:  + Maltose:  d Melezitose:  neg Sucrose:  + Trehalose:  d Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  neg α-Arab:  + Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  neg β-Glucuronidase:  d ArgDH:  neg GluDC:  + AlanineAA:  + GluGluAA:  d GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  + PyrrolidAA:  vr PheAA:  + PyrogluAA:  neg SerAA:  + TyrAA:  + AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg Pigment:  neg

    References

    SPECIFIC REFERENCES FOR PARABACTEROIDES JOHNSONII
  • Sakamoto2007a - Parabacteroides johnsonii sp. nov., isolated from human faeces.
  • Wexler2007 - Bacteroides : the Good, the Bad, and the Nitty-Gritty.
  • Bervoets2013 - Differences in gut microbiota composition between obese and lean children: a cross-sectional study
  • Kim2020a - Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension
  • MorenoArrones2019 - Analysis of the gut microbiota in alopecia areata: identification of bacterial biomarkers
  • Zhao2019a - Metagenome of Gut Microbiota of Children With Nonalcoholic Fatty Liver Disease
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PARABACTEROIDES JOHNSONII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Karlsson2013 - Gut metagenome in European women with normal, impaired and diabetic glucose control
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • Nielsen2014 - MetaHIT Consortium. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zupancic2012 - Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome.
  • ...............................
    • GENERAL REFERENCES FOR PARABACTEROIDES JOHNSONII
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021