Paraeggerthella hongkongensis

(aka Eggerthella hongkongensis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Paraeggerthella hongkongensis, (aka Eggerthella hongkongensis), is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 61.1-61.8%. Paraeggerthella hongkongensis is probably a rare gut coloniser. (Wurdemann2009; Lau2004; Wade2005Bergey)



  • This organism has been recovered from human faeces (Alkhalil2017), and clinical sources (blood - CCUG). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Wurdemann2009); (Lau2004); (Wade2005Bergey);
    Character Response
  • ⥅
  • Substrates assimilated or utilised:
  • rhamnose; methionine; threonine; valine; palatinose; UMP; urocanic acid;
  • Active enzymes:
  • arginine dihydrolase; catalase;
  • ±
  • Strain-dependent active enzymes:
  • Arg arylamidase; Leu arylamidase;
    • SPECIAL FEATURES (Wurdemann2009); (Lau2004);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Lau2004);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Cephalosporins:
  • cefotaxime;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;

  • Lau, S. K. P., Woo, P. C. Y., Woo, G. K. S., Fung, A. M. Y., Wong, M. K. M., Chan, K.-M., Tam, D. M. W., & Yuen, K.-Y. (2004). Eggerthella hongkongensis sp. nov. and eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia. Diagnostic Microbiology and Infectious Disease, 49(4), 255–263.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Eggerthellales Family:  Eggerthellaceae Genus:  Paraeggerthella Alt. name:  Eggerthella hongkongensis Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human faeces (Alkhalil2017), and clinical sources (blood - CCUG)
    DNA G+C(%):  61.1-61.8
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Glucose:  neg Mannose:  neg Xylose:  neg Trehalose:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Fucose:  neg Mannose:  neg Rhamnose:  + Trehalose:  neg Dextrin:  neg Met:  + Phe:  neg Thr:  + Val:  + Acetate:  neg Pyruvate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  neg G6PDH6PGDH:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  + GluDC:  neg AlanineAA:  neg ArgAA:  d(neg) GluGluAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  d LeuGlyAA:  neg ProAA:  neg PyrrolidAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  SensRNG: (0.25-0.5)
    cefotaxime:  R(>32)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  SensRNG: (0.75-1.5)
    metronidazole:  SensRNG: (0.25-1)

    References

    SPECIFIC REFERENCES FOR PARAEGGERTHELLA HONGKONGENSIS
  • Wurdemann2009 - Gordonibacter pamelaeae gen. nov., sp. nov., a new member of the Coriobacteriaceae isolated from a patient with Crohn's disease, and reclassification of Eggerthella hongkongensis Lau et al. 2006 as Paraeggerthella hongkongensis gen. nov., comb. nov.
  • Danylec2019b - Draft Genome Sequences of Type Strains of Gordonibacter faecihominis, Paraeggerthella hongkongensis, Parvibacter caecicola, Slackia equolifaciens, Slackia faecicanis, and Slackia isoflavoniconvertens.
  • Lau2004 - Eggerthella hongkongensis sp. nov. and eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia.
  • Wade2005Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Coriobacteriaceae, Genus VI. Eggerthella
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PARAEGGERTHELLA HONGKONGENSIS
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR PARAEGGERTHELLA HONGKONGENSIS
  • Alkhalil2017 - Bacterial involvements in ulcerative colitis: molecular and microbiological studies
    • Added: April 08, 2021