Paraprevotella clara

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Paraprevotella clara is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, bacterium. It has been detected in at least 11 gut microbiome compilation studies or metastudies. The DNA G+C content is 48.1%. Paraprevotella clara is a common gut coloniser. (Morotomi2009)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 91% of Europeans (unseenbio.com).
    • GENERAL CHARACTERISTICS (Morotomi2009);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; glucose; mannose; xylose; lactose; raffinose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; arabinosidase; acid phosphatase; α-galactosidase; β-galactosidase; Glu-Glu arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • Leu-Gly arylamidase;
    • SPECIAL FEATURES (Morotomi2009);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; succinate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Paraprevotella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  48.1
    		Aesculin:  neg Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  neg Xylose:  + Cellubiose:  neg Lactose:  + Maltose:  w Melezitose:  neg Sucrose:  neg Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg G6PDH6PGDH:  neg α-Arab:  + Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  w β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  + ArgAA:  neg CystineAA:  neg GluGluAA:  + GlyAA:  neg HisAA:  neg LeuAA:  neg LeuGlyAA:  d ProAA:  neg PyrrolidAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg ValAA:  neg AlkalineP:  + AcidP:  + Esterase(C4):  neg EstLip(C8):  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Succinate:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR PARAPREVOTELLA CLARA
  • Morotomi2009 - Paraprevotella clara gen. nov., sp. nov. and Paraprevotella xylaniphila sp. nov., members of the family 'Prevotellaceae' isolated from human faeces.
  • Feng2015 - Gut microbiome development along the colorectal adenoma-carcinoma sequence
  • AlpizarRodriguez2019 - Prevotella copri in individuals at risk for rheumatoid arthritis
  • Ishaq2017 - Molecular estimation of alteration in intestinal microbial composition in Hashimoto's thyroiditis patients
  • Kim2018 - Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure
  • Lv2016 - Alterations and correlations of the gut microbiome, metabolism and immunity in patients with primary biliary cirrhosis
  • Tan2018a - Altered gut microbiome and metabolome in patients with multiple system atrophy
  • Ye2018 - A metagenomic study of the gut microbiome in Behcet's disease
  • Ye2020 - Altered gut microbiome composition in patients with Vogt-Koyanagi-Harada disease
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PARAPREVOTELLA CLARA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • Nielsen2014 - MetaHIT Consortium. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
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    • Added: April 08, 2021