Parascardovia denticolens

(aka Bifidobacterium denticolens)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Parascardovia denticolens, (aka Bifidobacterium denticolens), is a Gram-positive, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 55%. Parascardovia denticolens is probably a rare gut coloniser. (Jian2002; Crociani1996)



  • This organism has been recovered from dental caries. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Is a rare opportunistic pathogen. A possible gut commensal.
    • QUIRKS
  • In 6% of Europeans (unseenbio.com). Rare coloniser. Found in human breast milk (Jeurink2013).
    • GENERAL CHARACTERISTICS (Jian2002); (Crociani1996);
    Character Response
  • Substrates hydrolysed or digested:
  • milk;
  • pH
  • Acidity tolerance:
  • tolerates pH 4.9; tolerates pH 8.0; Grows optimally at pH 6.7-7.3.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 25℃; grows at 30.5℃; grows at 42℃; Grows optimally at 37-39℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; ribose; dextrin; inulin; starch; lactose; maltose; melibiose; raffinose; sucrose; salicin;
  • ±
  • Strain-dependent acid from carbs:
  • L-arabinose; trehalose;
  • ⥅
  • Substrates assimilated or utilised:
  • L-asparagine; CO2 consumed;
    • SPECIAL FEATURES (Jian2002); (Crociani1996);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; lactate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✓
  • VP test:
  • active
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Bifidobacteriales Family:  Bifidobacteriaceae Genus:  Parascardovia Alt. name:  Bifidobacterium denticolens Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  dental caries
    DNA G+C(%):  55
    Opt. T:  37-39℃
    Lower T(℃):  25(neg)
    Mid T(℃):  30.5(+)
    High T(℃):  42(+)
    Opt. pH:  6.7-7.3
    pH 4.2-5.9:  4.9(+)
    pH 6.0-8.0:  8.0(+)
    		Gelatin:  neg Arginine:  neg Milk:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  d Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  neg Rhamnose:  neg Ribose:  + Xylose:  neg Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  d Dextrin:  + Inulin:  + Starch:  + Pectin:  neg Xylan:  neg Glycerol:  neg Mannitol:  neg Gluconate:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Lactate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Lactate:  + H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR PARASCARDOVIA DENTICOLENS
  • Jian2002 - Transfer of Bifidobacterium inopinatum and Bifidobacterium denticolens to Scardovia inopinata gen. nov., comb. nov., and Parascardovia denticolens gen. nov., comb. nov., respectively.
  • Crociani1996 - Bifidobacterium inopinatum sp. nov. and Bifidobacterium denticolens sp. nov., Two New Species Isolated from Human Dental Caries.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PARASCARDOVIA DENTICOLENS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: March 18, 2022