Parolsenella massiliensis

(aka Libanicoccus massiliensis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Parolsenella massiliensis, (aka Libanicoccus massiliensis), is a Gram-positive, non-spore-forming, anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 65.5%. Parolsenella massiliensis is probably a rare gut coloniser. (Sakamoto2019; Bilen2017e; Bilen2018c)



  • This organism has been recovered from human faeces (Bilen2017e). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Sakamoto2019); (Bilen2018c);
    Character Response
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 45℃; Grows optimally at 37℃.
  • Active enzymes:
  • Ala arylamidase; acid phosphatase; Arg arylamidase; esterase C4; esterase lipase C8; fucosidase; Gly arylamidase; His arylamidase; Leu arylamidase; Phe arylamidase; Pro arylamidase; Ser arylamidase; Tyr arylamidase; Val arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Sakamoto2019); (Bilen2018c);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Sakamoto2019);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • oxytetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin; kanamycin; neomycin;
  • Polypep/ketides:
  • bacitracin;
  • Heterocycles:
  • chloramphenicol; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Coriobacteriales Family:  Atopobiaceae Genus:  Parolsenella Alt. name:  Libanicoccus massiliensis Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human faeces (Bilen2017e)
    DNA G+C(%):  65.5
    Opt. T:  37℃
    Lower T(℃):  30(+)
    High T(℃):  45(+)
    Bile reaction(%):  20(+)
    		Aesculin:  vr Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Glucose:  neg Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Sucrose:  neg Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  + α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  + ArgAA:  + CystineAA:  neg GluGluAA:  neg GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  neg ProAA:  + PheAA:  + PyrogluAA:  neg SerAA:  + TyrAA:  + ValAA:  + AlkalineP:  w AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  + H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    penicillin:  Sens
    gentamicin:  Sens
    kanamycin:  Sens
    neomycin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    oxytetracycline:  Sens
    vancomycin:  Sens
    bacitracin:  Sens
    chloramphenicol:  Sens
    SXT:  Sens
    colistin:  Sens

    References

    SPECIFIC REFERENCES FOR PAROLSENELLA MASSILIENSIS
  • Sakamoto2019 - Comparative genomics of Parolsenella catena and Libanicoccus massiliensis: Reclassification of Libanicoccus massiliensis as Parolsenella massiliensis comb. nov.
  • Bilen2017e - 'Libanicoccus massiliensis' gen. nov., sp. nov., a new bacterium isolated from a stool sample from a pygmy woman.
  • Bilen2018c - Libanicoccus massiliensis gen. nov., sp. nov., a new bacterium isolated from human stool.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PAROLSENELLA MASSILIENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • GENERAL REFERENCES FOR PAROLSENELLA MASSILIENSIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: July 12, 2021