Peptacetobacter hiranonis

(aka Clostridium hiranonis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Peptacetobacter hiranonis, (aka Clostridium hiranonis), is a Gram-positive, spore-forming, strictly anaerobic, non-motile, rod-shaped - curved bacterium. It has been detected in at least 9 gut microbiome compilation studies or metastudies. The DNA G+C content is 31.1%. Peptacetobacter hiranonis is probably a common, although minor, coloniser of the gut. (Kitahara2001; Rainey2011fBergey)



  • This organism has been recovered from human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Kitahara2001); (Rainey2011fBergey);
    Character Response
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7.5-8.0.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; sucrose;
  • Active enzymes:
  • N-Ac β-glucosaminidase;
    • SPECIAL FEATURES (Kitahara2001); (Rainey2011fBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate (minor); isobutyrate (minor); isovalerate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Sulfate:
  • not reduced

  • Kitahara, M., Takamine, F., Imamura, T., & Benno, Y. (2001). Clostridium hiranonis sp. nov., a human intestinal bacterium with bile acid 7alpha-dehydroxylating activity. International Journal of Systematic and Evolutionary Microbiology, 51(Pt 1), 39–44.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Peptacetobacter Alt. name:  Clostridium hiranonis Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod - curved
    Health:   Positive
    Source:  human faeces
    DNA G+C(%):  31.1
    Opt. T:  37℃
    Opt. pH:  7.5-8.0
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  neg Amygdalin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg α-Arab:  neg Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg LeuAP:  neg AlanineAA:  neg ArgAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  neg PheAA:  neg PyrogluAA:  neg TyrAA:  neg AlkalineP:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  minor(+) Isobutyrate:  minor(+) Isovalerate:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR PEPTACETOBACTER HIRANONIS
  • Ridlon2006 - Bile salt biotransformations by human intestinal bacteria
  • Huang2019 - Analysis of microbiota in elderly patients with Acute Cerebral Infarction
  • Kitahara2001 - Clostridium hiranonis sp. nov., a human intestinal bacterium with bile acid 7-alpha-dehydroxylating activity.
  • Rainey2011fBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster XI
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PEPTACETOBACTER HIRANONIS
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • ...............................
    • GENERAL REFERENCES FOR PEPTACETOBACTER HIRANONIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021