Peptoclostridium acidaminophilum

(aka Eubacterium acidaminophilum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Peptoclostridium acidaminophilum, (aka Eubacterium acidaminophilum), is a Gram-positive, non-spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 44%. Peptoclostridium acidaminophilum is likely to be transient and not a long-term gut coloniser. (Galperin2016; Zindel1988)



  • This organism has been recovered from black, anaerobic mud, Germany. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Co-culture with Desulfovibrio vulgaris allows for fermentation of alanine, L-malate, valine and aspartate/H2.
    • GENERAL CHARACTERISTICS (Galperin2016); (Zindel1988);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 0% salt; grows weakly in 3% salt; Grows optimally with 1-2% salt.
  • pH
  • Acidity tolerance:
  • tolerates pH 6.5; tolerates pH 8.5; Grows optimally at pH 7.1-7.4.
  • 🌡
  • Temperature tolerance:
  • grows at 10℃; grows at 40℃; Grows optimally at 32-36℃.
  • ⥅
  • Substrates assimilated or utilised:
  • betaine; glycine; hippurate; sarcosine; serine; formate; pyruvate; Casamino acids;
    • SPECIAL FEATURES (Galperin2016); (Zindel1988);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; ammonia; COâ‚‚;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Sulfate:
  • not reduced
  • ✗
  • Thiosulfate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Peptostreptococcaceae Genus:  Peptoclostridium Alt. name:  Eubacterium acidaminophilum Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  black, anaerobic mud, Germany
    DNA G+C(%):  44
    Opt. T:  32-36℃
    Low T(℃):  10(+)
    Mid T(℃):  40(+)
    NaCl 0.5-2%:  0(neg)
    NaCl 3-5%:  3(w)
    Opt. pH:  7.1-7.4
    pH 6.0-8.0:  6.5(+)
    pH >8:  8.5(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Fructose:  neg Glucose:  neg Ethanol:  neg Methanol:  neg Ala:  neg β-Ala:  neg Arg:  neg Asp:  neg Betaine:  + Cys:  neg Glu:  neg Gly:  + Hippurate:  + His:  neg Ile:  neg Lys:  neg Met:  neg Orn:  neg Phe:  neg Pro:  neg Sarcosine:  + Ser:  + Thr:  neg Trp:  neg Tyr:  neg Citrate:  neg Formate:  + Fumarate:  neg Glycolate:  neg Lactate:  neg Pyruvate:  + Succinate:  neg D-Tartrate:  neg L-Tartrate:  neg

    References

    SPECIFIC REFERENCES FOR PEPTOCLOSTRIDIUM ACIDAMINOPHILUM
  • Galperin2016 - Phylogenomic analysis of the family Peptostreptococcaceae (Clostridium cluster XI) and proposal for reclassification of Clostridium litorale (Fendrich et al. 1991) and Eubacterium acidaminophilum (Zindel et al. 1989) as Peptoclostridium litorale gen. nov. comb. nov. and Peptoclostridium acidaminophilum comb. nov.
  • Zindel1988 - Eubacterium acidaminophilum sp. nov., a versatile amino acid-degrading anaerobe producing or utilizing H2 or formate.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PEPTOCLOSTRIDIUM ACIDAMINOPHILUM
  • New2022 - Collective effects of human genomic variation on microbiome function.
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    • Added: March 18, 2022