Peptoniphilus duerdenii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Peptoniphilus duerdenii is a Gram-positive, strictly anaerobic, coccus bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 33.4%. Peptoniphilus duerdenii is probably a rare gut coloniser. (UlgerToprak2012)



  • This organism has been recovered from human faeces and clinical sources (vaginal abscess). Is a rare opportunistic pathogen. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (UlgerToprak2012);
    Character Response
  • Active enzymes:
  • Arg arylamidase; Leu arylamidase; pyroGlu arylamidase;
    • SPECIAL FEATURES (UlgerToprak2012);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; butyrate; valerate (trace); isobutyrate (trace); succinate (trace); isovalerate (trace);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (UlgerToprak2012);
    Class Active Resistant
  • Aminoglycosides:
  • kanamycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Tissierellia Order:  Tissierellales Family:  Peptoniphilaceae Genus:  Peptoniphilus Gram stain:  + O2 Relation.:  strictly anaerobic Morphology:  Coccus
    Health:  Unknown
    Source:  human faeces and clinical sources (vaginal abscess)
    DNA G+C(%):  33.4
    		Aesculin:  neg Urea:  neg Gelatin:  neg Starch:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Mannose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  w Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  neg ArgAA:  + CystineAA:  neg GluGluAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  + LeuGlyAA:  neg ProAA:  neg PheAA:  neg PyrogluAA:  + SerAA:  neg TyrAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  neg Esterase(C4):  neg EstLip(C8):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  + Butyrate:  + Valerate:  trace(+) Isobutyrate:  trace(+) Succinate:  trace(+) Isovalerate:  trace(+) Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  S(1000; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(5; disc)
    colistin:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR PEPTONIPHILUS DUERDENII
  • UlgerToprak2012 - Peptoniphilus duerdenii sp. nov. and Peptoniphilus koenoeneniae sp. nov., isolated from human clinical specimens.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PEPTONIPHILUS DUERDENII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: December 15, 2021