Peptoniphilus gorbachii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Peptoniphilus gorbachii is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. Peptoniphilus gorbachii is probably a rare gut coloniser. (Song2007)



  • This organism has been recovered from clinical sources. Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Song2007);
    Character Response
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; Arg arylamidase; Gly arylamidase; His arylamidase; Leu arylamidase; Leu-Gly arylamidase; Phe arylamidase; Ser arylamidase; Tyr arylamidase;
    • SPECIAL FEATURES (Song2007);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (major); propionate (trace); butyrate;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Song2007);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; ampicillin-sulbactam; imipenem; penicillin G;
  • Cephalosporins:
  • cefazolin; cefoxitin;
  • Tetracyclines:
  • tigecycline;
  • Quinolines:
  • levofloxacin;
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Tissierellia Order:  Tissierellales Family:  Peptoniphilaceae Genus:  Peptoniphilus Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  clinical sources
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Coagulase:  neg β-Galactosidase:  neg β-Glucuronidase:  neg AlanineAA:  + ArgAA:  + GluGluAA:  neg GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  + PheAA:  + PyrogluAA:  neg SerAA:  + TyrAA:  + AlkalineP:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  S(0.015)
    amp-sulb:  S(0.25)
    penicillin_G:  S(0.06)
    imipenem:  S(0.062)
    cefazolin:  S(2)
    cefoxitin:  S(0.5)
    kanamycin:  S(1000; disc)
    levofloxacin:  R(16)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tigecycline:  SensRNG: (0.016-0.094)
    vancomycin:  S(1)
    metronidazole:  SensRNG: (0.25-4)
    colistin:  S(10; disc)

    References

    SPECIFIC REFERENCES FOR PEPTONIPHILUS GORBACHII
  • Song2007 - Peptoniphilus gorbachii sp. nov., Peptoniphilus olsenii sp. nov., and Anaerococcus murdochii sp. nov. isolated from clinical specimens of human origin.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PEPTONIPHILUS GORBACHII
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • deGoffau2013 - Fecal microbiota composition differs between children with β-cell autoimmunity and those without.
  • ...............................
    • Added: January 14, 2022