Peptoniphilus grossensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Peptoniphilus grossensis is a Gram-positive, spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 33.9%. Peptoniphilus grossensis is probably a rare gut coloniser. (Mishra2013d)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Mishra2013d);
    Character Response
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 30℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • mannose;
  • Active enzymes:
  • Arg arylamidase; His arylamidase; Leu arylamidase; Tyr arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • alkaline phosphatase;
    • SPECIAL FEATURES (Mishra2013d);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Mishra2013d);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; imipenem; penicillin G;
  • Cephalosporins:
  • cefalexin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • fosfomycin; metronidazole;
  • co-trimoxazole;
  • Vancomycins:
  • vancomycin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Tissierellia Order:  Tissierellales Family:  Peptoniphilaceae Genus:  Peptoniphilus Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  33.9
    Opt. T:  37℃
    Lower T(℃):  30(neg)
    High T(℃):  45(neg)
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Mannose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg ArgDH:  neg GluDC:  neg AlanineAA:  neg ArgAA:  + GluGluAA:  neg GlyAA:  neg HisAA:  + LeuAA:  + LeuGlyAA:  neg PyrrolidAA:  neg TyrAA:  + AlkalineP:  d
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    penicillin_G:  Sens
    imipenem:  Sens
    cefalexin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    fosfomycin:  Sens
    metronidazole:  Sens
    co-trimoxazole:  Res

    References

    SPECIFIC REFERENCES FOR PEPTONIPHILUS GROSSENSIS
  • Mishra2013d - Non contiguous-finished genome sequence and description of Peptoniphilus grossensis sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PEPTONIPHILUS GROSSENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR PEPTONIPHILUS GROSSENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021