Peptoniphilus pacaensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Peptoniphilus pacaensis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 49.4%. Peptoniphilus pacaensis is probably a rare gut coloniser.



  • This organism has been recovered from the vagina. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 4% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.5; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • ribose; D-tagatose; 5-ketogluconate;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; esterase C4; esterase lipase C8; naphthol-ASBI-P;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • amoxicillin; benzylpenicillin; ertapenem; imipenem;
  • Macrolides:
  • erythromycin;
  • Quinolines:
  • ofloxacin;
  • Aminoglycosides:
  • amikacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Tissierellia Order:  Tissierellales Family:  Peptoniphilaceae Genus:  Peptoniphilus Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  the vagina
    DNA G+C(%):  49.4
    Opt. T:  37℃
    NaCl 3-5%:  4(+)
    pH 6.0-8.0:  6.5(+)
    pH >8:  8.5(+)
    		Aesculin:  neg Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  neg Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Ribose:  + Sorbose:  neg D-Tagatose:  + Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  + Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg β-Galactosidase:  neg AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    benzyl-pen:  Sens
    ertapenem:  Sens
    imipenem:  Sens
    amikacin:  Res
    erythromycin:  Res
    ofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens
    rifampicin:  Sens
    metronidazole:  Sens

    References

    SPECIFIC REFERENCES FOR PEPTONIPHILUS PACAENSIS
  • Diop2019 - Description of three new Peptoniphilus species cultured in the vaginal fluid of a woman diagnosed with bacterial vaginosis: Peptoniphilus pacaensis sp. nov., Peptoniphilus raoultii sp. nov., and Peptoniphilus vaginalis sp. nov.
  • Diop2016a - 'Peptoniphilus pacaensis' sp. nov., a new species isolated from human female genital tract.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PEPTONIPHILUS PACAENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022