Phascolarctobacterium faecium

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Phascolarctobacterium faecium is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, pleiomorph rod-shaped bacterium. It has been detected in at least 12 gut microbiome compilation studies or metastudies. The DNA G+C content is 41-42%. Phascolarctobacterium faecium is probably a common, although minor, coloniser of the gut. (Dot1993; Sakamoto2020a; Stackebrandt2011Bergey)



  • This organism has been recovered from human faeces, and Koala faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Dot1993); (Sakamoto2020a); (Stackebrandt2011Bergey);
    Character Response
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 30-37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • succinate;
    • SPECIAL FEATURES (Dot1993); (Sakamoto2020a); (Stackebrandt2011Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • propionate (major);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Dot1993); (Sakamoto2020a); (Stackebrandt2011Bergey);
    Class Active Resistant
  • Aminoglycosides:
  • kanamycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

  • Hayashi, H., Sakamoto, M., & Benno, Y. (2002). Fecal microbial diversity in a strict vegetarian as determined by molecular analysis and cultivation. Microbiology and Immunology, 46(12), 819–831.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Acidaminococcales Family:  Acidaminococcaceae Genus:  Phascolarctobacterium Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Pleiomorph rod
    Health:  Unknown
    Source:  human faeces, and Koala faeces
    DNA G+C(%):  41-42
    Opt. T:  30-37℃
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  neg Glucose:  neg Mannose:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg PyrogluAA:  neg AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Propionate:  Major(+) Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Res
    colistin:  Sens

    References

    SPECIFIC REFERENCES FOR PHASCOLARCTOBACTERIUM FAECIUM
  • Dot1993 - Phascolarctobacterium faecium gen. nov, spec. nov., a Novel Taxon of the Sporomusa Group of Bacteria.
  • Sakamoto2020a - Dialister hominis sp. nov., isolated from human faeces.
  • Stackebrandt2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Veillonellaceae, Genus XVI. Phascolarctobacterium
  • Finegold2010 - Pyrosequencing study of fecal microflora of autistic and control children
  • Zhou2018 - Alterations in the gut microbiota of patients with acquired immune deficiency syndrome
  • Luna2016 - Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PHASCOLARCTOBACTERIUM FAECIUM
  • Jeong2021 - The effect of taxonomic classification by full-length 16S rRNA sequencing with a synthetic long-read technology
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Mangin2004 - Molecular inventory of faecal microflora in patients with Crohn's disease.
  • McLaughlin2010 - The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Salonen2014 - Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
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    • GENERAL REFERENCES FOR PHASCOLARCTOBACTERIUM FAECIUM
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021