Phenylobacterium falsum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Phenylobacterium falsum is a Gram-negative, non-spore-forming, strictly aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 66.9%. Phenylobacterium falsum is likely to be transient and not a long-term gut coloniser. (Tiago2005)



  • This organism has been recovered from human faeces and groundwater from Portugal. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe; unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Tiago2005);
    Character Response
  • Substrates hydrolysed or digested:
  • hippurate; urea;
  • 🧂
  • Salt tolerance:
  • tolerates 7% salt; Grows optimally with 0% salt.
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 6.0; doesn't tolerate pH 10; Grows optimally at pH 7.5-8.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 20℃; doesn't grow at 45℃; Grows optimally at 35℃.
  • ⥅
  • Substrates assimilated or utilised:
  • alanine; arginine; glutamate; isoleucine; proline; 2-ketoglutarate; pyruvate; succinate; glutamine;
  • Active enzymes:
  • catalase; β-galactosidase; oxidase; urease;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Tiago2005);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; penicillin G;
  • Cephalosporins:
  • ceftazidime; cephalothin;
  • Tetracyclines:
  • doxycycline; tetracycline;
  • Quinolines:
  • ofloxacin;
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; kanamycin; streptomycin;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • colistin; polymyxin B;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Alphaproteobacteria Order:  Caulobacterales Family:  Caulobacteraceae Genus:  Phenylobacterium Gram stain:  neg O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and groundwater from Portugal
    DNA G+C(%):  66.9
    Opt. T:  35℃
    Lower T(℃):  20(neg)
    High T(℃):  45(neg)
    NaCl >6%:  7(+)
    Opt. pH:  7.5-8
    pH 6.0-8.0:  6.0(neg)
    pH >8:  10(neg)
    		Aesculin:  neg Urea:  + Gelatin:  neg Starch:  neg Casein:  neg DNA:  neg Hippurate:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Glucose:  neg Xylose:  neg Sucrose:  neg Glycerol:  neg Ala:  + Arg:  + Asp:  neg Cys:  neg Glu:  + Gly:  neg His:  neg Ile:  + Lys:  neg Met:  neg Orn:  neg Phe:  neg Pro:  + Ser:  neg Thr:  neg Val:  neg Citrate:  neg Pyruvate:  + Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  + β-Galactosidase:  + DNAse:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  R(25; disc)
    penicillin_G:  R(10U)
    ceftazidime:  R(30; disc)
    cephalothin:  R(30; disc)
    gentamicin:  S(10; disc)
    kanamycin:  S(30; disc)
    streptomycin:  S(10; disc)
    nalidixic-acid:  R(30; disc)
    ofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(30; disc)
    tetracycline:  S(30; disc)
    chloramphenicol:  S(30; disc)
    colistin:  S(50; disc)
    polymyxin_B:  S(300U)

    References

    SPECIFIC REFERENCES FOR PHENYLOBACTERIUM FALSUM
  • Tiago2005 - Phenylobacterium falsum sp. nov., an Alphaproteobacterium isolated from a nonsaline alkaline groundwater, and emended description of the genus Phenylobacterium.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PHENYLOBACTERIUM FALSUM
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
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    • Added: December 15, 2021