Prevotella baroniae

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Prevotella baroniae is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 52%. Prevotella baroniae is probably a rare gut coloniser. (Hahnke2016; Downes2005)



  • This organism has been recovered from human oral cavity, blood and human faeces. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Hahnke2016); (Downes2005);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; cellubiose; lactose; maltose; melibiose; raffinose; sucrose; salicin;
    • SPECIAL FEATURES (Hahnke2016); (Downes2005);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; isobutyrate (minor); succinate; isovalerate (minor);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Goldstein2018a);
    Class Active Resistant
  • Penicillins:
  • ampicillin-sulbactam; imipenem; piperacillin-tazobactam;
  • Tetracyclines:
  • tigecycline;
  • Quinolines:
  • moxifloxacin;
  • Heterocycles:
  • metronidazole;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Prevotella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  human oral cavity, blood and human faeces
    DNA G+C(%):  52
    Bile reaction(%):  20(neg)
    		Aesculin:  + Urea:  neg Gelatin:  w Arginine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Mannitol:  neg Sorbitol:  neg Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg G6PDH6PGDH:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Isobutyrate:  minor(+) Succinate:  + Isovalerate:  minor(+) Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amp-sulb:  S(MIC50): 0.5, MIC90: 1, RNG: (0.03–2)
    piper-taz:  S(MIC50): 0.03, MIC90: 0.03, RNG: (0.03–0.25)
    imipenem:  S(MIC50): 0.06, MIC90: 0.125, RNG: (0.03–0.125)
    moxifloxacin:  S(MIC50): 2, MIC90: 4, RNG: (0.25–4)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tigecycline:  S(MIC50): 0.5, MIC90: 0.5, RNG: (0.03–1)
    metronidazole:  S(MIC50): 0.5, MIC90: 1, RNG: (0.25–2)
    clindamycin:  R(MIC50): 0.03, MIC90: >32, RNG: (0.03->32)

    References

    SPECIFIC REFERENCES FOR PREVOTELLA BARONIAE
  • Hahnke2016 - Description of Proteiniphilum saccharofermentans sp. nov., Petrimonas mucosa sp. nov. and Fermentimonas caenicola gen. nov., sp. nov., isolated from mesophilic laboratory-scale biogas reactors, and emended description of the genus Proteiniphilum.
  • Downes2005 - Prevotella marshii sp. nov. and Prevotella baroniae sp. nov., isolated from the human oral cavity.
  • Goldstein2018a - Comparative In Vitro Activities of Relebactam, Imipenem, the Combination of the Two, and Six Comparator Antimicrobial Agents against 432 Strains of Anaerobic Organisms, Including Imipenem-Resistant Strains.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PREVOTELLA BARONIAE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
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    • Added: December 15, 2021