Prevotella bryantii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Prevotella bryantii is a Gram-negative, non-spore-forming, anaerobic, non-motile, oval-shaped bacterium. It has been detected in at least 5 gut microbiome compilation studies or metastudies. The DNA G+C content is 40-43%. Prevotella bryantii is probably a rare gut coloniser. (Avgustin1997; Shah2010Bergeys)



  • This organism has been recovered from human faeces, and rumen. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Avgustin1997); (Shah2010Bergeys);
    Character Response
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; L-arabinose; fructose; galactose; glucose; mannose; xylose; aesculin; inulin; xylan; cellubiose; lactose; maltose; melibiose; raffinose; sucrose; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • cysteine; methionine;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; β-glucosidase; Leu-Gly arylamidase; xylosidase;
  • ±
  • Strain-dependent active enzymes:
  • α-glucosidase;
    • SPECIAL FEATURES (Avgustin1997); (Shah2010Bergeys);
    Character Response
  • ✓
  • Metabolites produced:
  • formate (trace); acetate; propionate (trace); isobutyrate (trace); succinate; isovalerate (trace);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced
  • NOTES

    Phenotypically similar strains have been
    reported from man, but these have been assigned to either
    Prevotella oris or Prevotella buccae.

  • Prevotella species at mucosal sites to localized and systemic disease, including periodontitis, bacterial vaginosis, rheumatoid arthritis, metabolic disorders and low_grade systemic inflammation. Intriguingly, Prevotella abundance is reduced within the lung microbiota of patients with asthma and chronic obstructive pulmonary disease. Increased Prevotella abundance is associated with augmented T helper type 17 (Th17) _mediated mucosal inflammation, which is in line with the marked capacity of Prevotella in driving Th17 immune responses in vitro. Studies indicate that Prevotella predominantly activate Toll_like receptor 2, leading to production of Th17_polarizing cytokines by antigen_presenting cells, including interleukin_23 (IL_23) and IL_1. Furthermore, Prevotella stimulate epithelial cells to produce IL_8, IL_6 and CCL20, which can promote mucosal Th17 immune responses and neutrophil recruitment. Prevotella_mediated mucosal inflammation leads to systemic dissemination of inflammatory mediators, bacteria and bacterial products, which in turn may affect systemic disease outcomes. [PMID: 28542929]

  • GutFeeling KnowledgeBase COMMENTS [Website]

    Prevotella species are anaerobic Gram_negative bacteria of the Bacteroidetes phylum, which also includes the clinically important genera Bacteroides and Porphyromonas. Prevotella strains are classically considered commensal bacteria due to their extensive presence in the healthy human body and their rare involvement in infections. Only a few strains have been reported to give rise to opportunistic endogenous infections, including chronic infections, abscesses and anaerobic pneumonia. [PMID: 28542929]

  • Li, Q., Wang, C., Tang, C., Li, N., & Li, J. (2012). Molecular-phylogenetic characterization of the microbiota in ulcerated and non-ulcerated regions in the patients with Crohn’s disease. PloS One, 7(4), e34939.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Prevotella Gram stain:  neg O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Oval-shaped Pigment:  neg
    Health:  Unknown
    Source:  human faeces, and rumen
    DNA G+C(%):  40-43
    Bile reaction(%):  20(neg)
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + L-Arabinose:  + Fructose:  + D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  w Ribose:  neg Sorbose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  neg Lactose:  + Maltose:  + Melibiose:  + Sucrose:  + Trehalose:  neg Aesculin:  + Inulin:  + Xylan:  + Adonitol:  neg D-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg NAc-α-GA:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Cys:  + Met:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg G6PDH6PGDH:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  vr β-Galactosidase:  vr α-Glucosidase:  d β-Glucosidase:  + β-Glucuronidase:  neg Xylosidase:  + ArgDH:  neg GluDC:  neg AlanineAA:  + GluGluAA:  neg GlyAA:  neg LeuAA:  neg LeuGlyAA:  + PyrrolidAA:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  trace(+) Acetate:  + Propionate:  trace(+) Isobutyrate:  trace(+) Succinate:  + Isovalerate:  trace(+) Indole:  neg Pigment:  neg

    References

    SPECIFIC REFERENCES FOR PREVOTELLA BRYANTII
  • Avgustin1997 - Phenotypic Diversity among Ruminal Isolates of Prevotella ruminicola: Proposal of Prevotella brevis sp. nov., Prevotella bryantii sp. nov., and Prevotella albensis sp. nov. and Redefinition of Prevotella ruminicola.
  • Shah2010Bergeys - Bergey's manual of systematic bacteriology. Vol. 4, The Bacteroidetes. Family Prevotellaceae, Genus I. Prevotella
  • Li2012 - Molecular-phylogenetic characterization of the microbiota in ulcerated and non-ulcerated regions in the patients with Crohn's disease
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PREVOTELLA BRYANTII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: April 08, 2021