Prevotella buccalis

(aka Bacteroides buccalis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Prevotella buccalis, (aka Bacteroides buccalis), is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 7 gut microbiome compilation studies or metastudies. The DNA G+C content is 45-46%. Prevotella buccalis is probably a common, although minor, coloniser of the gut. (Shah1990; Shah1981)



  • This organism has been recovered from human faeces (Bilen2018e), dental plaque and umbilical drainage. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Is a rare opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Shah1990); (Shah1981);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; cellubiose; lactose; maltose; sucrose; salicin;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; esterase C4; esterase lipase C8; fucosidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; phosphoamidase;
    • SPECIAL FEATURES (Shah1990); (Shah1981);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (major); lactate (minor); succinate (major);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Schaumann1999); (Shah1981);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; imipenem;
  • penicillin G;
  • Macrolides:
  • erythromycin;
  • Quinolines:
  • gatifloxacin; trovafloxacin;
  • Aminoglycosides:
  • kanamycin;
  • Polypep/ketides:
  • rifampicin;
  • bacitracin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Prevotella Alt. name:  Bacteroides buccalis Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces (Bilen2018e), dental plaque and umbilical drainage
    DNA G+C(%):  45-46
    		Aesculin:  + Gelatin:  neg Starch:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Rhamnose:  neg Xylose:  neg Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Sucrose:  + Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    G6PDH6PGDH:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg Xylosidase:  neg GlyAP:  neg AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg Phosphoamidase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  Major(+) Lactate:  minor(+) Succinate:  Major(+) Indole:  neg Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Augmentin:  S(MIC50): 0.5, MIC90: 2, RNG: (0.06-8)
    penicillin_G:  Res
    imipenem:  S(MIC50): 0.06, MIC90: 0.25, RNG: (0.03-1)
    kanamycin:  Res
    erythromycin:  S(MIC50): 1, MIC90: 2, RNG: (0.125-8)
    ciprofloxacin:  Var(MIC50): 1, MIC90: 16, RNG: (0.25-32)
    gatifloxacin:  S(MIC50): 0.25, MIC90: 2, RNG: (0.125-4)
    trovafloxacin:  S(MIC50): 0.5, MIC90: 1, RNG: (0.125-2)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Res
    bacitracin:  Res
    rifampicin:  Sens
    metronidazole:  S(MIC50): 0.25, MIC90: 1, RNG: (0.125-1)
    clindamycin:  S(MIC50): 0.03, MIC90: 0.5, RNG: (0.03-4)
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR PREVOTELLA BUCCALIS
  • Shah1990 - Notes: Prevotella, a New Genus To Include Bacteroides melaninogenicus and Related Species Formerly Classified in the Genus Bacteroides.
  • Schaumann1999 - In vitro activities of gatifloxacin, two other quinolones, and five nonquinolone antimicrobials against obligately anaerobic bacteria.
  • Shah1981 - Bacteroides buccalis, sp. nov., Bacteroides denticola, sp. nov., and Bacteroides pentosaceus, sp. nov., new species of the genus Bacteroides from the oral cavity.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PREVOTELLA BUCCALIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • GENERAL REFERENCES FOR PREVOTELLA BUCCALIS
  • Bilen2018e - Description of the human gut microbiota by culturomics
    • Added: December 15, 2021