Prevotella conceptionensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Prevotella conceptionensis is a Gram-negative, non-spore-forming, anaerobic, non-motile, pleiomorphic bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. Prevotella conceptionensis is probably a rare gut coloniser. (LaScola2011)



  • This organism has been recovered from human faeces. Is a rare opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS
    Character Response
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose; aesculin; cellubiose; lactose; maltose; raffinose; sucrose; trehalose;
    • SPECIAL FEATURES (LaScola2011);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;

  • Prevotella species at mucosal sites to localized and systemic disease, including periodontitis, bacterial vaginosis, rheumatoid arthritis, metabolic disorders and low_grade systemic inflammation. Intriguingly, Prevotella abundance is reduced within the lung microbiota of patients with asthma and chronic obstructive pulmonary disease. Increased Prevotella abundance is associated with augmented T helper type 17 (Th17) _mediated mucosal inflammation, which is in line with the marked capacity of Prevotella in driving Th17 immune responses in vitro. Studies indicate that Prevotella predominantly activate Toll_like receptor 2, leading to production of Th17_polarizing cytokines by antigen_presenting cells, including interleukin_23 (IL_23) and IL_1. Furthermore, Prevotella stimulate epithelial cells to produce IL_8, IL_6 and CCL20, which can promote mucosal Th17 immune responses and neutrophil recruitment. Prevotella_mediated mucosal inflammation leads to systemic dissemination of inflammatory mediators, bacteria and bacterial products, which in turn may affect systemic disease outcomes. [PMID: 28542929]

  • GutFeeling KnowledgeBase COMMENTS [Website]

    Prevotella species are anaerobic Gram_negative bacteria of the Bacteroidetes phylum, which also includes the clinically important genera Bacteroides and Porphyromonas. Prevotella strains are classically considered commensal bacteria due to their extensive presence in the healthy human body and their rare involvement in infections. Only a few strains have been reported to give rise to opportunistic endogenous infections, including chronic infections, abscesses and anaerobic pneumonia. [PMID: 28542929]

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Prevotella Gram stain:  neg O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Pleiomorphic
    Health:  Unknown
    Source:  human faeces
    Bile reaction(%):  20(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  + Mannose:  + Cellubiose:  + Lactose:  + Maltose:  + Sucrose:  + Trehalose:  + Aesculin:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +

    References

    SPECIFIC REFERENCES FOR PREVOTELLA CONCEPTIONENSIS
  • LaScola2011 - Burden of emerging anaerobes in the MALDI-TOF and 16S rRNA gene sequencing era.
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PREVOTELLA CONCEPTIONENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
  • ...............................
    • Added: April 08, 2021