Prevotella jejuni

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Prevotella jejuni is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 41.7%. Prevotella jejuni is probably a rare gut coloniser. (Hedberg2013)



  • This organism has been recovered from the jejunum of a child with coeliac disease. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Hedberg2013);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • pH
  • Acidity tolerance:
  • grows weakly at pH 5.5; grows weakly at pH 7.5; Grows optimally at pH 6-7.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; mannose; lactose; maltose; raffinose; sucrose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; acid phosphatase; Arg arylamidase; N-Ac β-glucosaminidase; fucosidase; β-galactosidase; α-glucosidase; Leu-Gly arylamidase; naphthol-ASBI-P;
  • ±
  • Strain-dependent active enzymes:
  • α-galactosidase; Leu arylamidase;
    • SPECIAL FEATURES (Hedberg2013);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; succinate; isovalerate (minor); ammonia;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • Haemolysis:
  • present
  • ✗
  • Nitrate:
  • not reduced
  • ✓
  • Pigments:
  • produced
    • RESPONSE TO ANTIBIOTICS (Hedberg2013);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Aminoglycosides:
  • kanamycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • bile; colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Prevotella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  +
    Health:  Unknown
    Source:  the jejunum of a child with coeliac disease
    DNA G+C(%):  41.7
    Opt. T:  37℃
    Opt. pH:  6-7
    pH 4.2-5.9:  5.5(w)
    pH 6.0-8.0:  7.5(w)
    		Aesculin:  neg Urea:  neg Gelatin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  + Maltose:  + Melezitose:  neg Sucrose:  + Trehalose:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg α-Arab:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  d β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  + ArgAA:  + CystineAA:  neg GluGluAA:  neg GlyAA:  neg HisAA:  w LeuAA:  d LeuGlyAA:  + ProAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg ValAA:  neg AlkalineP:  + AcidP:  + Esterase(C4):  neg EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Succinate:  + Isovalerate:  minor(+) Ammonia:  + Indole:  neg Pigment:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  R(0.003-0.015)
    kanamycin:  S(1000; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  R(5; disc)
    colistin:  S(10; disc)
    Bile:  S(1000; disc)

    References

    SPECIFIC REFERENCES FOR PREVOTELLA JEJUNI
  • Hedberg2013 - Prevotella jejuni sp. nov., isolated from the small intestine of a child with coeliac disease.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PREVOTELLA JEJUNI
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Urban2020 - Altered Fecal Microbiome Years after Traumatic Brain Injury
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    • Added: January 14, 2022