Prevotella micans

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Prevotella micans is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 46%. Prevotella micans is probably a rare gut coloniser. (Downes2009b)



  • This organism has been recovered from an oral cavity. Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Downes2009b);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 37℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; cellubiose; lactose; maltose; melibiose; raffinose; sucrose; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • cellubiose; lactose; mannose; raffinose; salicin; sucrose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; N-Ac β-glucosaminidase; fucosidase; α-galactosidase; β-galactosidase; α-glucosidase; Leu-Gly arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • β-glucosidase; Glu-Glu arylamidase;
    • SPECIAL FEATURES (Downes2009b);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; isobutyrate (minor); succinate; isovalerate; indole;
  • ✗
  • Nitrate:
  • not reduced
  • Pigments:
  • yellow-orange
    • RESPONSE TO ANTIBIOTICS (Downes2009b);
    Class Active Resistant
  • Aminoglycosides:
  • kanamycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Prevotellaceae Genus:  Prevotella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  yellow-orange
    Health:  Unknown
    Source:  an oral cavity
    DNA G+C(%):  46
    Mid T(℃):  37(+)
    Bile reaction(%):  20(neg)
    		Aesculin:  neg Urea:  neg Gelatin:  + Arginine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Mannitol:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Mannose:  + Cellubiose:  + Lactose:  + Raffinose:  + Sucrose:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  d AlanineAA:  + GluGluAA:  d LeuGlyAA:  + AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Isobutyrate:  minor(+) Succinate:  + Isovalerate:  + Indole:  + Pigment:  yellow-orange
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  R(1000; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  R(5; disc)
    colistin:  S(10; disc)

    References

    SPECIFIC REFERENCES FOR PREVOTELLA MICANS
  • Downes2009b - Prevotella micans sp. nov., isolated from the human oral cavity.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PREVOTELLA MICANS
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • ...............................
    • Added: January 19, 2022