Propionibacterium acidifaciens

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Propionibacterium acidifaciens is a Gram-positive, non-spore-forming, anaerobic, non-motile, pleiomorph rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 70%. Propionibacterium acidifaciens is probably a rare gut coloniser. (Downes2009a)



  • This organism has been recovered from oral carious lesions. Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Downes2009a);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 37℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; rhamnose; ribose; lactose; maltose; melibiose; raffinose; sucrose; mannitol;
  • Active enzymes:
  • Arg arylamidase; α-galactosidase; β-galactosidase; α-glucosidase; Leu arylamidase; Phe arylamidase; Pro arylamidase; Tyr arylamidase;
    • SPECIAL FEATURES (Downes2009a);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (major); propionate (major); succinate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Downes2009a);
    Class Active Resistant
  • Aminoglycosides:
  • kanamycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Propionibacteriales Family:  Propionibacteriaceae Genus:  Propionibacterium Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Pleiomorph rod
    Health:  Unknown
    Source:  oral carious lesions
    DNA G+C(%):  70
    Mid T(℃):  37(+)
    		Aesculin:  neg Urea:  neg Gelatin:  neg Arginine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  + Glucose:  + Mannose:  + Rhamnose:  + Ribose:  + Cellubiose:  neg Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Mannitol:  + Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + ArgAA:  + LeuAA:  + ProAA:  + PheAA:  + TyrAA:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  Major(+) Propionate:  Major(+) Succinate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  S(1000; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(5; disc)
    colistin:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR PROPIONIBACTERIUM ACIDIFACIENS
  • Downes2009a - Propionibacterium acidifaciens sp. nov., isolated from the human mouth.
  • Munson2004 - Molecular analysis of the microflora associated with dental caries.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PROPIONIBACTERIUM ACIDIFACIENS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: January 14, 2022