Pseudescherichia vulneris

(aka Escherichia vulneris)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Pseudescherichia vulneris, (aka Escherichia vulneris), is a Gram-negative, non-spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 58.5-58.7%. Pseudescherichia vulneris is probably a rare gut coloniser. (Farmer1985; Brenner1982a; Scheutz2005Bergey)



  • This organism has been recovered from clinical sources (wound, blood, urine - CCUG) and human faeces (CCUG; including ulcerative colitis patients - Alkhalil2017). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Farmer1985); (Brenner1982a); (Scheutz2005Bergey);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; glucose; mannose; rhamnose; xylose; cellubiose; maltose; melibiose; raffinose; trehalose; mannitol;
  • ±
  • Strain-dependent acid from carbs:
  • α-methyl glucoside; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • malonate; mucate;
  • ±
  • Strain-dependent substrate utilisation:
  • acetate;
  • Active enzymes:
  • catalase; lycine decarboxylase;
  • ±
  • Strain-dependent active enzymes:
  • arginine dihydrolase;
    • SPECIAL FEATURES (Farmer1985); (Brenner1982a); (Scheutz2005Bergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✓
  • Methyl red test:
  • active
  • ✗
  • VP test:
  • not active
  • ✓
  • ONPG test:
  • active
  • ±
  • KCN growth:
  • most strains inhibited
  • ✓
  • NO3➔NO2:
  • reduced
  • Pigments:
  • yellow (variable)
    • RESPONSE TO ANTIBIOTICS (Brenner1982a); (Scheutz2005Bergey);
    Class Active Resistant
  • Penicillins:
  • ampicillin;
  • penicillin G;
  • Cephalosporins:
  • cefamandole; cefoxitin; cephalothin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • nalidixic-acid;
  • Aminoglycosides:
  • amikacin; gentamicin; kanamycin; tobramycin;
  • Heterocycles:
  • chloramphenicol; nitrofurantoin; trimethoprim-sulfamethoxazole;
  • Miscellaneous antibiotics:
  • polymyxin B;
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Enterobacterales Family:  Enterobacteriaceae Genus:  Pseudescherichia Alt. name:  Escherichia vulneris Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod Pigment:  yellow (variable)
    Health:  Unknown
    Source:  clinical sources (wound, blood, urine - CCUG) and human faeces (CCUG; including ulcerative colitis patients - Alkhalil2017)
    DNA G+C(%):  58.5-58.7
    		Aesculin:  neg Urea:  neg Gelatin:  neg DNA:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  + Xylose:  + Cellubiose:  + Lactose:  neg Maltose:  + Melibiose:  + Sucrose:  neg Trehalose:  + Adonitol:  neg D-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  + Sorbitol:  neg Me-α-D-Glc:  d(neg) Salicin:  d(neg)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Acetate:  d Citrate:  neg Malonate:  + Mucate:  d(+) D-Tartrate:  neg L-Tartrate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + ArgDH:  d(neg) LysDC:  + OrnDC:  neg Phe deaminase:  neg DNAse:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg Pigment:  yellow (variable)
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  S(10; disc)
    carbenicil:  Var(MIC50): 100; disc), MIC90: Var(100; disc
    penicillin_G:  R(10U)
    cefamandole:  S(30; disc)
    cefoxitin:  S(30; disc)
    cephalothin:  S(30; disc)
    amikacin:  S(10; disc)
    gentamicin:  S(10; disc)
    kanamycin:  S(30; disc)
    tobramycin:  S(10; disc)
    erythromycin:  R(15; disc, variable)
    nalidixic-acid:  S(30; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(30; disc)
    chloramphenicol:  S(30; disc)
    nitrofurantoin:  S(300; disc)
    SXT:  S(25; disc)
    clindamycin:  R(2; disc)
    polymyxin_B:  S(300U)

    References

    SPECIFIC REFERENCES FOR PSEUDESCHERICHIA VULNERIS
  • Alnajar2017 - Phylogenomics and comparative genomic studies delineate six main clades within the family Enterobacteriaceae and support the reclassification of several polyphyletic members of the family.
  • Gryp2020 - Isolation and Quantification of Uremic Toxin Precursor-Generating Gut Bacteria in Chronic Kidney Disease Patients
  • Farmer1985 - Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens.
  • Brenner1982a - Escherichia vulneris : a New Species of Enterobacteriaceae Associated with Human Wounds.
  • Scheutz2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Gammaproteobacteria Part B. Family Enterobacteriaceae, Genus I. Escherichia
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PSEUDESCHERICHIA VULNERIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • ...............................
    • GENERAL REFERENCES FOR PSEUDESCHERICHIA VULNERIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
  • Alkhalil2017 - Bacterial involvements in ulcerative colitis: molecular and microbiological studies
    • Added: July 12, 2021