Pseudoclavibacter sp. Timone

(aka Pseudoclavibacter massiliense)

Bacteria


General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview


  • Pseudoclavibacter sp. Timone, (aka Pseudoclavibacter massiliense), is a Gram-positive, non-spore-forming, aerobic, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 67%. Pseudoclavibacter sp. Timone is probably a rare gut coloniser. (Manaia2004)



  • This organism has been recovered from human faeces and clinical sources. Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.

  • GENERAL CHARACTERISTICS (Manaia2004);
    Character Response
  • Active enzymes:
  • catalase;

  • SPECIAL FEATURES (Manaia2004);
    Character Response
  • Metabolites produced:
  • acetate (minor);
  • Metabolites not produced:
  • indole;

  • RESPONSE TO ANTIBIOTICS (Lemaitre2011);
    Class Active Resistant
  • Penicillins:
  • amoxicillin;
  • Tetracyclines:
  • doxycycline;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • co-trimoxazole; metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.


  • Details


    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Micrococcales Family:  Microbacteriaceae Genus:  Pseudoclavibacter Alt. name:  Pseudoclavibacter massiliense Gram stain:  + O2 Relation.:  aerobic Spore:  No spore Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and clinical sources
    DNA G+C(%):  67

    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  +

    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    Acetate:  minor(+) Indole:  neg

    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(≤2)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(≤4)
    vancomycin:  S(≤4)
    rifampicin:  S(≤4)
    metronidazole:  Res
    co-trimoxazole:  Res
    clindamycin:  Res

    References


    SPECIFIC REFERENCES FOR PSEUDOCLAVIBACTER SP. TIMONE
  • Lemaitre2011 - Pseudoclavibacter-like subcutaneous infection: a case report.
  • Manaia2004 - Gulosibacter molinativorax gen. nov., sp. nov., a molinate-degrading bacterium, and classification of 'Brevibacterium helvolum' DSM 20419 as Pseudoclavibacter helvolus gen. nov., sp. nov.
  • ...............................
  • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PSEUDOCLAVIBACTER SP. TIMONE
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................