Pseudoclostridium thermosuccinogenes

(aka Clostridium thermosuccinogenes)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Pseudoclostridium thermosuccinogenes, (aka Clostridium thermosuccinogenes), is a Gram-negative, spore-forming, anaerobic, motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 35.9%. Pseudoclostridium thermosuccinogenes is likely to be transient and not a long-term gut coloniser. (Rainey2011cBergey; Drent1991)



  • This organism has been recovered from human faeces, cow manure and food sources. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • High optimum growth temperature so unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Rainey2011cBergey); (Drent1991);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • milk;
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 40℃; grows at 60℃; Grows optimally at 58℃.
  • ⥅
  • Substrates assimilated or utilised:
  • cellubiose; fructose; galactose; glucose; inulin; lactose; maltose; ribose; raffinose; starch; sucrose; xylose;
  • ±
  • Strain-dependent substrate utilisation:
  • mannitol; sorbitol;
    • SPECIAL FEATURES (Rainey2011cBergey); (Drent1991);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; lactate; succinate; Hâ‚‚S; Hâ‚‚;
  • ✗
  • Nitrate:
  • not reduced
  • ✓
  • Thiosulfate:
  • reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Oscillospiraceae Genus:  Pseudoclostridium Alt. name:  Clostridium thermosuccinogenes Gram stain:  neg O2 Relation.:  anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, cow manure and food sources
    DNA G+C(%):  35.9
    Opt. T:  58℃
    Mid T(℃):  40(+)
    High T(℃):  60(+)
    Opt. pH:  7.0
    		Aesculin:  + Gelatin:  w Milk:  curdle
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Ribose:  + Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Raffinose:  + Sucrose:  + Cellulose:  neg Glycerol:  neg Inulin:  + Mannitol:  d(neg) Methanol:  neg Pectin:  neg Sorbitol:  d(neg) Starch:  + Xylan:  neg Glu:  neg Citrate:  neg Pyruvate:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Lactate:  + Succinate:  + H2S:  + H2:  +

    References

    SPECIFIC REFERENCES FOR PSEUDOCLOSTRIDIUM THERMOSUCCINOGENES
  • Rainey2011cBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster III
  • Drent1991 - Fermentation of Inulin by Clostridium thermosuccinogenes sp. nov., a Thermophilic Anaerobic Bacterium Isolated from Various Habitats.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR PSEUDOCLOSTRIDIUM THERMOSUCCINOGENES
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
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    • Added: October 28, 2021