Romboutsia ilealis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Romboutsia ilealis is a Gram-variable, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 28.1%. Romboutsia ilealis is probably a rare gut coloniser. (Gerritsen2014)



  • This organism has been recovered from rat gastrointestinal tract and human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Gerritsen2014);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 1% salt;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 5% bile
  • pH
  • Acidity tolerance:
  • tolerates pH 6.5-8.0; Grows optimally at pH 7.0-7.5.
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fucose; glucose; raffinose; sucrose;
    • SPECIAL FEATURES (Gerritsen2014);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; lactate; H₂S; CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Sulfate:
  • not reduced
  • ✗
  • Thiosulfate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Heterocycles:
  • metronidazole;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Peptostreptococcaceae Genus:  Romboutsia Gram stain:  vr O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  rat gastrointestinal tract and human faeces
    DNA G+C(%):  28.1
    Opt. T:  37℃
    Lower T(℃):  30(+)
    High T(℃):  45(+)
    NaCl 0.5-2%:  1(+)
    Opt. pH:  7.0-7.5
    pH 6.0-8.0:  6.5-8.0(+)
    Bile reaction(%):  5(neg)
    		Urea:  neg Gelatin:  neg Starch:  neg Tween:  80(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  w L-Arabinose:  neg Fructose:  neg Fucose:  + D-Fucose:  neg Galactose:  w Glucose:  + Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  neg Turanose:  neg Amygdalin:  neg Cellulose:  neg Glycogen:  neg Inulin:  w Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Lactate:  + H2S:  + CO2:  + H2:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  S(<0.016)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    metronidazole:  S(<0.016)
    clindamycin:  S(0.125)

    References

    SPECIFIC REFERENCES FOR ROMBOUTSIA ILEALIS
  • Gerritsen2014 - Characterization of Romboutsia ilealis gen. nov., sp. nov., isolated from the gastro-intestinal tract of a rat, and proposal for the reclassification of five closely related members of the genus Clostridium into the genera Romboutsia gen. nov., Intestinibacter gen. nov., Terrisporobacter gen. nov. and Asaccharospora gen. nov.
  • Bojovic2020 - Gut Microbiota Dysbiosis Associated With Altered Production of Short Chain Fatty Acids in Children With Neurodevelopmental Disorders
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ROMBOUTSIA ILEALIS
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • ...............................
    • Added: December 15, 2021