Rothia aeria

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Rothia aeria is a Gram-positive, non-spore-forming, aerobic, coccus bacterium. It has been detected in at least 10 gut microbiome compilation studies or metastudies. The DNA G+C content is 57.8%. Rothia aeria is probably a common, although minor, coloniser of the gut. (Li2004)



  • This organism has been recovered from air samples, clinical sources (sputum, blood, peritonean fluid - CCUG) and human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Li2004);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; maltose; sucrose; trehalose;
  • ⥅
  • Substrates assimilated or utilised:
  • arbutin; dextrin; fructose; glucose; glycerol; maltose; maltotriose; mannose; melezitose; methyl-α-glucoside; salicin; sucrose; trehalose; D-turanose; methyl-β-glucoside; psicose; palatinose; 2-hydroxybutyrate; L-lactate;
  • Active enzymes:
  • Ala arylamidase; Ala-Phe-Pro arylamidase; catalase; α-glucosidase; β-glucosidase; Gly arylamidase; Leu arylamidase; Leu-Gly arylamidase; pyrrolidine arylamidase;
    • SPECIAL FEATURES (Li2004);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • VP test:
  • active
  • ✓
  • Nitrate:
  • reduced

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Micrococcales Family:  Micrococcaceae Genus:  Rothia Gram stain:  + O2 Relation.:  aerobic Spore:  No spore Morphology:  Coccus
    Health:  Unknown
    Source:  air samples, clinical sources (sputum, blood, peritonean fluid - CCUG) and human faeces
    DNA G+C(%):  57.8
    		Aesculin:  + Urea:  neg Gelatin:  neg Hippurate:  neg Tween:  40(neg) 80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Glucose:  + Mannose:  neg Ribose:  neg D-Tagatose:  neg Xylose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Sucrose:  + Trehalose:  + Dextrin:  neg Glycogen:  neg D-Arabitol:  neg Mannitol:  neg Sorbitol:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  + Maltotriose:  + Melezitose:  + Melibiose:  neg Raffinose:  neg Sucrose:  + D-Turanose:  + Trehalose:  + N_Acetyl_glucosamine:  neg Amygdalin:  neg D-Arabitol:  neg Arbutin:  + Dextrin:  + Gluconate:  neg Glycerol:  + Glycogen:  neg Inositol:  neg Inulin:  neg Mannitol:  neg Me-α-D-Glc:  + Salicin:  + Sorbitol:  neg Xylitol:  neg Ala:  neg D-Ala:  neg Glu:  neg Ser:  neg Acetate:  neg 3-Hydroxybutyrate:  neg L-Malate:  neg Propionate:  neg Pyruvate:  neg Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg β-Mannosidase:  neg ArgDH:  neg GluDC:  neg AlanineAA:  + AlaPheProAA:  + GluGluAA:  neg GlyAA:  + LeuAA:  + LeuGlyAA:  + PyrrolidAA:  + AlkalineP:  neg AcidP:  vr Esterase(C4):  vr EstLip(C8):  vr Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg

    References

    SPECIFIC REFERENCES FOR ROTHIA AERIA
  • Li2004 - Rothia aeria sp. nov., Rhodococcus baikonurensis sp. nov. and Arthrobacter russicus sp. nov., isolated from air in the Russian space laboratory Mir.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ROTHIA AERIA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Li2019b - Disordered intestinal microbes are associated with the activity of Systemic Lupus Erythematosus
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • PerezBrocal2015 - Metagenomic Analysis of Crohn's Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
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    • Added: April 08, 2021