Ruminiclostridium cellulolyticum

(aka Clostridium cellulolyticum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Ruminiclostridium cellulolyticum, (aka Clostridium cellulolyticum), is a Gram-positive, spore-forming, anaerobic, motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 41%. Ruminiclostridium cellulolyticum is likely to be transient and not a long-term gut coloniser. (Yutin2013; Zhang2018; Petitdemange1984)



  • This organism has been recovered from decayed grass. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Yutin2013); (Zhang2018); (Petitdemange1984);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; cellulose;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 45℃; Grows optimally at 32-35℃.
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; fructose; glucose; xylose; cellulose; xylan; cellubiose;
    • SPECIAL FEATURES (Yutin2013); (Zhang2018); (Petitdemange1984);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; lactate; ethanol; COâ‚‚; Hâ‚‚;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • NO3➔NO2:
  • not reduced
  • ✗
  • Thiosulfate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Ruminiclostridium Alt. name:  Clostridium cellulolyticum Gram stain:  + O2 Relation.:  anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  decayed grass
    DNA G+C(%):  41
    Opt. T:  32-35℃
    Lower T(℃):  25(+)
    High T(℃):  45(+)
    		Aesculin:  + Gelatin:  neg Starch:  neg Casein:  neg Arginine:  neg Milk:  neg Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + Fructose:  + Galactose:  w Glucose:  + Mannose:  w Rhamnose:  neg Ribose:  w Sorbose:  neg Xylose:  + Cellubiose:  + Lactose:  neg Maltose:  neg Melezitose:  neg Sucrose:  neg Trehalose:  neg Amygdalin:  neg Cellulose:  + Glycogen:  neg Inulin:  neg Xylan:  + Adonitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Lactate:  neg Pyruvate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Lactate:  + Ethanol:  + CO2:  + H2:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR RUMINICLOSTRIDIUM CELLULOLYTICUM
  • Yutin2013 - A genomic update on clostridial phylogeny: Gram-negative spore formers and other misplaced clostridia.
  • Zhang2018 - Petroclostridium xylanilyticum gen. nov., sp. nov., a xylan-degrading bacterium isolated from an oilfield, and reclassification of clostridial cluster III members into four novel genera in a new Hungateiclostridiaceae fam. nov.
  • Wang2019a - Alterations in Gut Glutamate Metabolism Associated with Changes in Gut Microbiota Composition in Children with Autism Spectrum Disorder
  • Petitdemange1984 - Clostridium cellulolyticum sp. nov. , a Cellulolytic, Mesophilic: Species from Decayed Grass
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR RUMINICLOSTRIDIUM CELLULOLYTICUM
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: March 18, 2022