Selenomonas flueggei

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Selenomonas flueggei is a Gram-negative, non-spore-forming, strictly anaerobic, motile, rod-shaped - curved bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 56-58%. Selenomonas flueggei is probably a rare gut coloniser. (moore1987)



  • This organism has been recovered from gingival crevices. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS (moore1987);
    Character Response
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37-45℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; lactose; maltose; melibiose; raffinose; sucrose; inositol; mannitol; sorbitol;
  • ±
  • Strain-dependent acid from carbs:
  • ribose;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; esterase C4; esterase lipase C8; α-galactosidase; α-glucosidase;
    • SPECIAL FEATURES (moore1987);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; ammoniaminor;
  • ✗
  • Metabolites not produced:
  • H₂S; H₂; indole;
  • ✗
  • Haemolysis:
  • absent
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (moore1987);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Selenomonadales Family:  Selenomonadaceae Genus:  Selenomonas Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod - curved
    Health:  Unknown
    Source:  gingival crevices
    DNA G+C(%):  56-58
    Opt. T:  37-45℃
    		Aesculin:  neg Gelatin:  neg Hippurate:  neg Milk:  neg Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  d Sorbose:  neg Xylose:  neg Cellubiose:  neg Lactose:  + Maltose:  d(+) Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  neg Amygdalin:  neg Dextrin:  neg Aesculin:  neg Glycogen:  neg Starch:  neg Pectin:  neg Xylan:  neg Adonitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  d(+) Mannitol:  d(+) Sorbitol:  + Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  neg α-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg Trypsin:  neg ArgAA:  neg CystineAA:  neg LeuAA:  neg ProAA:  neg AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  + H2S:  neg Ammonia:  minor H2:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  S(MIC50): 0.25, MIC90: -, RNG: (0.25-4)
    erythromycin:  S(3)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(6)
    chloramphenicol:  S(12)
    clindamycin:  S(1.6)

    References

    SPECIFIC REFERENCES FOR SELENOMONAS FLUEGGEI
  • moore1987 - Selenomonas noxia sp. nov., Selenomonas flueggei sp. nov., Selenomonas infelix sp. nov., Selenomonas dianae sp. nov., and Selenomonas artemidis sp. nov., from the Human Gingival Crevice
  • Gao2020 - Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co-Metabolism in Patients With Alcoholic Hepatitis
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR SELENOMONAS FLUEGGEI
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: October 10, 2022