Selenomonas noxia

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Selenomonas noxia is a Gram-negative, non-spore-forming, strictly anaerobic, motile, rod-shaped - curved bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 56-58%. Selenomonas noxia is probably a rare gut coloniser. (Shouche2011Bergey; moore1987)



  • This organism has been recovered from human faeces and gingival crevices. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Shouche2011Bergey); (moore1987);
    Character Response
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 25℃; grows at 45℃; Grows optimally at 30-37℃.
  • ±
  • Strain-dependent acid from carbs:
  • fructose; glucose;
  • ⥅
  • Substrates assimilated or utilised:
  • fructose; glucose; mannose; sorbitol; sorbose; fumarate;
  • ±
  • Strain-dependent substrate utilisation:
  • sucrose;
  • ±
  • Strain-dependent active enzymes:
  • cystine arylamidase; β-galactosidase;
    • SPECIAL FEATURES (Shouche2011Bergey); (moore1987);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; lactate;
  • ✗
  • Metabolites not produced:
  • H₂S; ammonia; indole;
  • ✗
  • Haemolysis:
  • absent
  • ±
  • Nitrate:
  • reduced by few strains
    • RESPONSE TO ANTIBIOTICS (moore1987);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Selenomonadales Family:  Selenomonadaceae Genus:  Selenomonas Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod - curved
    Health:  Unknown
    Source:  human faeces and gingival crevices
    DNA G+C(%):  56-58
    Opt. T:  30-37℃
    Lower T(℃):  25(neg)
    High T(℃):  45(+)
    		Aesculin:  neg Urea:  neg Gelatin:  neg Hippurate:  neg Milk:  neg Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  d Galactose:  neg Glucose:  d Mannose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Amygdalin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Pectin:  neg Xylan:  neg Adonitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Fructose:  + Glucose:  + Mannose:  + Sorbose:  + Sucrose:  d Sorbitol:  + Fumarate:  + Lactate:  neg Pyruvate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  d(w) α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg ValAP:  neg CystineAA:  d(neg) GlyAA:  neg LeuGlyAA:  neg PyrrolidAA:  neg PheAA:  neg SerAA:  neg AlkalineP:  w AcidP:  w Esterase(C4):  w EstLip(C8):  w Lecithinase:  neg Lipase(C14):  w
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  + Lactate:  + H2S:  neg Ammonia:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  S(MIC50): 0.25, MIC90: -, RNG: (0.25-4)
    erythromycin:  S(3)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(6)
    chloramphenicol:  S(12)
    clindamycin:  S(1.6)

    References

    SPECIFIC REFERENCES FOR SELENOMONAS NOXIA
  • Shouche2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Veillonellaceae, Genus XXI. Selenomonas
  • moore1987 - Selenomonas noxia sp. nov., Selenomonas flueggei sp. nov., Selenomonas infelix sp. nov., Selenomonas dianae sp. nov., and Selenomonas artemidis sp. nov., from the Human Gingival Crevice
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR SELENOMONAS NOXIA
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: December 15, 2021