Sneathia vaginalis

(aka Sneathia amnii)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Sneathia vaginalis, (aka Sneathia amnii), is a Gram-negative, non-spore-forming, anaerobic, non-motile, pleiomorph rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 28%. Sneathia vaginalis is probably a rare gut coloniser. (Harwich2012)



  • This organism has been recovered from human clinical specimens (mid-vaginal wall, amniotic fluid). Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • QUIRKS
  • Sneathia vaginalis same as 'Sneathia amnii'. Simple metabolism, utilising glycogen, maltose and glucose.
    • GENERAL CHARACTERISTICS (Harwich2012);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; glycogen; maltose;
    • SPECIAL FEATURES (Harwich2012);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • Haemolysis:
  • alpha
    • RESPONSE TO ANTIBIOTICS (Harwich2012);
    Class Active Resistant
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • minocycline;
  • tetracycline;
  • Quinolines:
  • ciprofloxacin; nalidixic-acid;
  • Aminoglycosides:
  • kanamycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol; metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Fusobacteria Class:  Fusobacteriia Order:  Fusobacteriales Family:  Leptotrichiaceae Genus:  Sneathia Alt. name:  Sneathia amnii Gram stain:  neg O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Pleiomorph rod
    Health:  Unknown
    Source:  human clinical specimens (mid-vaginal wall, amniotic fluid)
    DNA G+C(%):  28
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Galactose:  neg Glucose:  + Mannose:  neg Maltose:  + Glycogen:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Var(MIC50): 9.8), MIC90: Var(9.8
    kanamycin:  S(6)
    erythromycin:  R(>10)
    ciprofloxacin:  R(25)
    nalidixic-acid:  R(312)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  S(0.97)
    tetracycline:  R(>50)
    vancomycin:  S(1.0)
    rifampicin:  S(0.4)
    chloramphenicol:  S(1.25)
    metronidazole:  S(0.5)
    clindamycin:  S(5)

    References

    SPECIFIC REFERENCES FOR SNEATHIA VAGINALIS
  • Harwich2012 - Genomic sequence analysis and characterization of Sneathia amnii sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR SNEATHIA VAGINALIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
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    • Added: May 15, 2022