Sphingobacterium thalpophilum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Sphingobacterium thalpophilum is a Gram-negative, non-spore-forming, aerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 45.0%. Sphingobacterium thalpophilum is likely to be transient and not a long-term gut coloniser. (Takeuchi1992)



  • This organism has been recovered from clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Takeuchi1992);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; gelatin;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 5℃; grows at 37℃; grows at 42℃;
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; fructose; glucose; rhamnose; xylose; cellubiose; lactose; maltose; raffinose; sucrose; trehalose; adonitol; glycerol; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • 3-hydroxybutyrate; NH4+ consumed;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; acid phosphatase; Arg arylamidase; N-Ac β-glucosaminidase; Asp arylamidase; catalase; β-galactosidase; α-glucosidase; Gly arylamidase; His arylamidase; Leu arylamidase; Leu-Gly arylamidase; oxidase; pyrrolidine arylamidase; Ser arylamidase; urease; Val arylamidase; naphthol-ASBI-P;
  • ±
  • Strain-dependent active enzymes:
  • chymotrypsin; fucosidase; α-galactosidase; β-glucosidase; trypsin;
    • SPECIAL FEATURES (Takeuchi1992);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • KCN growth:
  • inhibited (0.008%)
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrite:
  • not reduced
  • ✓
  • NO3➔NO2:
  • reduced
  • Pigments:
  • yellow
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • ampicillin; carbenicillin;
  • Cephalosporins:
  • cephalothin;
  • Tetracyclines:
  • tetracycline;
  • Aminoglycosides:
  • amikacin; gentamicin; kanamycin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Sphingobacteriia Order:  Sphingobacterales Family:  Sphingobacteriaceae Genus:  Sphingobacterium Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  yellow
    Health:  Unknown
    Source:  clinical sources
    DNA G+C(%):  45.0
    Low T(℃):  5(neg)
    Mid T(℃):  37(+)
    High T(℃):  42(+)
    		Aesculin:  + Gelatin:  + Starch:  neg Casein:  neg Tyrosine:  neg Tween:  20(+) 80(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + Fructose:  + Glucose:  + Rhamnose:  + Xylose:  + Cellubiose:  + Lactose:  + Maltose:  + Sucrose:  + Trehalose:  + Adonitol:  + Dulcitol:  neg Glycerol:  + Inositol:  neg Mannitol:  neg Sorbitol:  neg Ethanol:  neg Gluconate:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Citrate:  neg 3-Hydroxybutyrate:  + Malonate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  + Ac-β-glcamnd:  + α-Fucosidase:  d α-Galactosidase:  d β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  d β-Glucuronidase:  neg α-Mannosidase:  neg Xylosidase:  neg ArgDH:  neg Chymotrypsin:  d LysDC:  neg OrnDC:  neg Phe deaminase:  neg Trypsin:  d AlanineAA:  + ArgAA:  + AspAA:  + CystineAA:  neg GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  + PyrrolidAA:  + SerAA:  + ValAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  neg EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg Pigment:  yellow
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  R(64)
    carbenicil:  R(32-128)
    cephalothin:  R(128)
    amikacin:  R(>32)
    gentamicin:  R(>32)
    kanamycin:  R(>32)
    tobramycin:  R(>32)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Res
    rifampicin:  SensRNG: (0.5-2)
    chloramphenicol:  R(>8)

    References

    SPECIFIC REFERENCES FOR SPHINGOBACTERIUM THALPOPHILUM
  • Takeuchi1992 - Proposals of Sphingobacterium faecium sp. nov., Sphingobacterium piscium sp. nov., Sphingobacterium heparinum comb. nov., sphingobacterium thalpophilum comb. nov. and two genospecies of the genus Sphingobacterium, and synonymy of Flavobacterium yabuuchiae and Sphingobacterium spiritivorum.
  • Holmes1983 - Flavobacterium thalpophilum, a New Species Recovered from Human Clinical Material
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR SPHINGOBACTERIUM THALPOPHILUM
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022