Stenotrophomonas acidaminiphila

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Stenotrophomonas acidaminiphila is a Gram-negative, non-spore-forming, strictly aerobic, motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 66.9%. Stenotrophomonas acidaminiphila is likely to be transient and not a long-term gut coloniser. (Assih2002)



  • This organism has been recovered from sludge reactor, clinical sources (trachea, urine, blood - CCUG) and detected in human faeces (Bilen2018e). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. It is an opportunistic pathogen. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe; unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Assih2002);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • pH
  • Acidity tolerance:
  • tolerates pH 5.0; tolerates pH 9.0; Grows optimally at pH 6.0-7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; grows at 42℃; Grows optimally at 30-35℃.
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; fructose; glucose; maltose; mannose; alanine; D-alanine; arginine; aspartate; cysteine; glutamate; histidine; isoleucine; leucine; phenylalanine; proline; serine; threonine; tyrosine; valine; acetate; fumarate; DL-lactate; pyruvate; glutamine; L-asparagine; Casamino acids;
  • Active enzymes:
  • catalase; oxidase;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Nitrate:
  • reduced
  • ✓
  • Nitrite:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Assih2002);
    Class Active Resistant
  • Penicillins:
  • piperacillin; piperacillin-tazobactam;
  • amoxicillin; amoxicillin-clavulanic acid; imipenem;
  • Cephalosporins:
  • ceftazidime;
  • cefotaxime; cephalothin;
  • Quinolines:
  • ciprofloxacin; ofloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin; netilmycin; tobramycin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Xanthomonadales Family:  Xanthomonadaceae Genus:  Stenotrophomonas Gram stain:  neg O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  sludge reactor, clinical sources (trachea, urine, blood - CCUG) and detected in human faeces (Bilen2018e)
    DNA G+C(%):  66.9
    Opt. T:  30-35℃
    Lower T(℃):  20(+)
    High T(℃):  42(+)
    Opt. pH:  6.0-7.0
    pH 4.2-5.9:  5.0(+)
    pH >8:  9.0(+)
    		Aesculin:  + Tween:  80(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Melibiose:  neg Raffinose:  neg Sucrose:  neg D-Turanose:  neg Trehalose:  neg N_Acetyl_glucosamine:  + Adonitol:  neg Amygdalin:  neg D-Arabitol:  neg L-Arabitol:  neg Arbutin:  neg Dulcitol:  neg Erythritol:  neg Ethanol:  neg Gluconate:  neg Glycerol:  neg Glycogen:  neg Inositol:  neg Inulin:  neg Mannitol:  neg Me-α-D-Glc:  neg Propanol:  neg Salicin:  neg Sorbitol:  neg Starch:  neg Xylitol:  neg Ala:  + D-Ala:  + Arg:  + Asp:  + Cys:  + Glu:  + Gly:  neg His:  + Ile:  + Leu:  + Lys:  neg Met:  neg Orn:  neg Phe:  + Pro:  + Ser:  + Thr:  + Trp:  neg Tyr:  + Val:  + Acetate:  + Adipate:  neg Benzoate:  vr Butyrate:  neg Caprate:  neg Fumarate:  + 2-Ketogluconate:  neg 5-Ketogluconate:  neg DL-Lactate:  + Malate:  neg Phenylacetate:  neg Propionate:  neg Pyruvate:  + Succinate:  vr
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  R(25; disc)
    Augmentin:  Res
    piperacillin:  S(75; disc)
    piper-taz:  Sens
    ticarcillin:  Var(MIC50): 75; disc), MIC90: Var(75; disc
    imipenem:  R(10; disc)
    cefotaxime:  R(30; disc)
    ceftazidime:  S(30; disc)
    cephalothin:  R(30; disc)
    amikacin:  S(30; disc)
    gentamicin:  S(10U)
    netilmycin:  S(30; disc)
    tobramycin:  S(10; disc)
    ciprofloxacin:  S(5; disc)
    ofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    SXT:  S(25; disc)
    colistin:  S(300U)

    References

    SPECIFIC REFERENCES FOR STENOTROPHOMONAS ACIDAMINIPHILA
  • Assih2002 - Stenotrophomonas acidaminiphila sp. nov., a strictly aerobic bacterium isolated from an upflow anaerobic sludge blanket (UASB) reactor.
  • Patil2016 - Genome Sequence of Type Strains of Genus Stenotrophomonas.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR STENOTROPHOMONAS ACIDAMINIPHILA
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • PerezBrocal2015 - Metagenomic Analysis of Crohn's Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers
  • ...............................
    • GENERAL REFERENCES FOR STENOTROPHOMONAS ACIDAMINIPHILA
  • Bilen2018e - Description of the human gut microbiota by culturomics
    • Added: January 06, 2022