Stomatobaculum longum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Stomatobaculum longum is a Gram-variable, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 55.0-55.3%. Stomatobaculum longum is probably a common, although minor, coloniser of the gut. (Sizova2013)



  • This organism has been recovered from human faeces and subgingival dental plaque. Is a rare opportunistic pathogen. A possible gut commensal.
    • QUIRKS
  • In 27% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Sizova2013);
    Character Response
  • 💧
  • Bile tolerance:
  • Doesn't tolerate bile
  • pH
  • Acidity tolerance:
  • tolerates pH 4.9; tolerates pH 7.5;
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 42℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; maltose; sucrose;
  • ⥅
  • Substrates assimilated or utilised:
  • dextrin; fructose; galactose; glucose; maltose; raffinose; sucrose; glutamate; serine; citrate; fumarate; malate; pyruvate; glutamine; L-asparagine; α-ketobutyrate;
    • SPECIAL FEATURES (Sizova2013);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate; lactate; isovalerate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Sizova2013);
    Class Active Resistant
  • Penicillins:
  • ampicillin; penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Aminoglycosides:
  • kanamycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Stomatobaculum Gram stain:  vr O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces and subgingival dental plaque
    DNA G+C(%):  55.0-55.3
    Opt. T:  37℃
    Lower T(℃):  30(+)
    High T(℃):  42(+)
    pH 4.2-5.9:  4.9(+)
    pH 6.0-8.0:  7.5(+)
    Bile reaction(%):  neg
    		Aesculin:  neg Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Glucose:  + Mannose:  neg Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Sucrose:  + Trehalose:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Fructose:  + Galactose:  + Glucose:  + Maltose:  + Raffinose:  + Sucrose:  + Dextrin:  + Starch:  neg Glu:  + Ser:  + Citrate:  + Fumarate:  + Malate:  + Pyruvate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  + Lactate:  + Isovalerate:  + Indole:  neg Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  S(10; disc)
    penicillin:  S(2U)
    kanamycin:  S(1000; disc)
    erythromycin:  S(60; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(30; disc)
    vancomycin:  S(5; disc)
    rifampicin:  S(15; disc)
    metronidazole:  S(50; disc)
    SXT:  R(25; disc)
    colistin:  S(10; disc)

    References

    SPECIFIC REFERENCES FOR STOMATOBACULUM LONGUM
  • Sizova2013 - Stomatobaculum longum gen. nov., sp. nov., an obligately anaerobic bacterium from the human oral cavity.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR STOMATOBACULUM LONGUM
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • ...............................
    • Added: December 15, 2021