Streptobacillus moniliformis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Streptobacillus moniliformis is a Gram-negative, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 26.3%. Streptobacillus moniliformis is likely to be transient and not a long-term gut coloniser. (Woo2014; Eisenberg2015)



  • This organism has been recovered from rat nasopharynx. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: zoonotic pathogen). Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Woo2014); (Eisenberg2015);
    Character Response
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 35-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose;
  • Active enzymes:
  • Ala-Phe-Pro arylamidase; chymotrypsin; esterase lipase C8; Phe arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • alkaline phosphatase; acid phosphatase; esterase C4; Leu arylamidase;
    • SPECIAL FEATURES (Eisenberg2015);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ±
  • Haemolysis:
  • alpha (strain dependent)
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Woo2014); (Eisenberg2015);
    Class Active Resistant
  • Penicillins:
  • meropenem;
  • Macrolides:
  • azithromycin; erythromycin; telithromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin; nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; streptomycin;
  • Heterocycles:
  • chloramphenicol;
  • trimethoprim-sulfamethoxazole;
  • Miscellaneous antibiotics:
  • clindamycin; telithromycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Fusobacteria Class:  Fusobacteriia Order:  Fusobacteriales Family:  Leptotrichiaceae Genus:  Streptobacillus Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  rat nasopharynx
    DNA G+C(%):  26.3
    Opt. T:  35-37℃
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  + Trypsin:  neg AlaPheProAA:  + CystineAA:  neg LeuAA:  d PheAA:  + ValAA:  neg AlkalineP:  d AcidP:  d Esterase(C4):  d EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    meropenem:  S(0.25)
    gentamicin:  S(0.125)
    streptomycin:  S(1)
    azithromycin:  S(0.0625)
    erythromycin:  S(0.5)
    telithromycin:  S(0.125)
    ciprofloxacin:  S(1)
    nalidixic-acid:  S(2)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(0.125)
    chloramphenicol:  S(1)
    SXT:  R(>8/256)
    clindamycin:  S(0.25)

    References

    SPECIFIC REFERENCES FOR STREPTOBACILLUS MONILIFORMIS
  • Woo2014 - Streptobacillus hongkongensis sp. nov., isolated from patients with quinsy and septic arthritis, and emended descriptions of the genus Streptobacillus and Streptobacillus moniliformis.
  • Eisenberg2015 - Streptobacillus felis sp. nov., isolated from a cat with pneumonia, and emended descriptions of the genus Streptobacillus and of Streptobacillus moniliformis.
  • Yu2015 - Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR STREPTOBACILLUS MONILIFORMIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: March 18, 2022