Streptococcus macedonicus

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Streptococcus macedonicus is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 38%. Streptococcus macedonicus is probably a rare gut coloniser. (Poyart2002; Schlegel2003; Flint1999; Manachini2002)



  • This organism has been recovered from Greek Kasseri cheese. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Poyart2002); (Schlegel2003); (Flint1999); (Manachini2002);
    Character Response
  • Substrates hydrolysed or digested:
  • milk;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate bile
  • 🌡
  • Temperature tolerance:
  • grows weakly at 30℃; Grows optimally at 37-42℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; cellubiose; lactose; maltose; raffinose; sucrose; N-Ac glucosamine;
  • ±
  • Strain-dependent acid from carbs:
  • melibiose; arbutin; salicin;
  • Active enzymes:
  • Ala-Phe-Pro arylamidase; α-galactosidase; Leu arylamidase;
    • SPECIAL FEATURES (Poyart2002); (Schlegel2003);
    Character Response
  • ✓
  • VP test:
  • active
  • Haemolysis:
  • alpha
  • ✗
  • Pigments:
  • not produced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Streptococcaceae Genus:  Streptococcus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus Pigment:  neg
    Health:  Unknown
    Source:  Greek Kasseri cheese
    DNA G+C(%):  38
    Opt. T:  37-42℃
    Lower T(℃):  30(w)
    Bile reaction(%):  neg
    		Aesculin:  neg Urea:  neg Hippurate:  neg Milk:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  + Gentiobiose:  neg Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  d Sucrose:  + Trehalose:  neg Turanose:  neg Amygdalin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  d(neg) Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  + Salicin:  d(neg)
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg α-Galactosidase:  + β-Galactosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg β-Mannosidase:  neg ArgDH:  neg AlaPheProAA:  + GlyTrpAA:  neg LeuAA:  + PyrrolidAA:  neg AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  neg

    References

    SPECIFIC REFERENCES FOR STREPTOCOCCUS MACEDONICUS
  • Poyart2002 - Taxonomic dissection of the Streptococcus bovis group by analysis of manganese-dependent superoxide dismutase gene (sodA) sequences: reclassification of 'Streptococcus infantarius subsp. coli' as Streptococcus lutetiensis sp. nov. and of Streptococcus bovis biotype II.2 as Streptococcus pasteurianus sp. nov.
  • Schlegel2003 - Reappraisal of the taxonomy of the Streptococcus bovis/Streptococcus equinus complex and related species: description of Streptococcus gallolyticus subsp. gallolyticus subsp. nov., S. gallolyticus subsp. macedonicus subsp. nov. and S. gallolyticus subsp. pasteurianus subsp. nov.
  • Tsakalidou1998 - Identification of streptococci from Greek Kasseri cheese and description of Streptococcus macedonicus sp. nov.
  • Flint1999 - Streptococcus waius sp. nov., a thermophilic Streptococcus from a biofilm.
  • Manachini2002 - Comparison between Streptococcus macedonicus and Streptococcus waius strains and reclassification of Streptococcus waius (Flint et at. 1999) as Streptococcus macedonicus (Tsakalidou et al. 1998).
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR STREPTOCOCCUS MACEDONICUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • New2022 - Collective effects of human genomic variation on microbiome function.
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    • Added: March 18, 2022