Streptococcus pasteurianus

(aka Streptococcus gallolyticus subsp. pasteurianus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Streptococcus pasteurianus, (aka Streptococcus gallolyticus subsp. pasteurianus), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 8 gut microbiome compilation studies or metastudies. Streptococcus pasteurianus is probably a common, although minor, coloniser of the gut. (Poyart2002; Whiley2011Bergey; Beck2008; Schlegel2003)



  • This organism has been recovered from human faeces, clinical sources (pharynx, blood, urine - CCUG) and tooth surfaces. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). It is an opportunistic pathogen. A possible gut commensal. Robust growth can have negative consequences for gut health.
    • GENERAL CHARACTERISTICS (Poyart2002); (Whiley2011Bergey); (Beck2008); (Schlegel2003);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 6.5% salt;
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; lactose; maltose; sucrose; trehalose; α-methyl glucoside; N-Ac glucosamine;
  • ±
  • Strain-dependent acid from carbs:
  • D-tagatose; melezitose; melibiose; raffinose;
  • ⥅
  • Substrates assimilated or utilised:
  • melibiose;
  • Active enzymes:
  • Ala-Phe-Pro arylamidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase; Leu arylamidase; β-mannosidase;
    • SPECIAL FEATURES (Poyart2002); (Whiley2011Bergey); (Beck2008); (Schlegel2003);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • VP test:
  • active
  • Haemolysis:
  • alpha
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced

  • Streptococci are members of the normal flora. Virulence factors of group A streptococci include (1) M protein and lipoteichoic acid for attachment; (2) a hyaluronic acid capsule that inhibits phagocytosis; (3) other extracellular products, such as pyrogenic (erythrogenic) toxin, which causes the rash of scarlet fever; and (4) streptokinase, streptodornase (DNase B), and streptolysins. Some strains are nephritogenic. Immune-mediated sequelae do not reflect dissemination of bacteria. Nongroup A strains have no defined virulence factors. In humans, diseases associated with the streptococci occur chiefly in the respiratory tract, bloodstream, or as skin infections. [https://www.ncbi.nlm.nih.gov/books/NBK7611/]

  • GutFeeling KnowledgeBase COMMENTS [Website]

    The genus Streptococcus , a heterogeneous group of Gram-positive bacteria, has broad significance in medicine and industry. Various streptococci are important ecologically as part of the normal microbial flora of animals and humans; some can also cause diseases that range from subacute to acute or even chronic. Among the significant human diseases attributable to streptococci are scarlet fever, rheumatic heart disease, glomerulonephritis, and pneumococcal pneumonia. Streptococci are essential in industrial and dairy processes and as indicators of pollution. [https://www.ncbi.nlm.nih.gov/books/NBK7611/]

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Streptococcaceae Genus:  Streptococcus Alt. name:  Streptococcus gallolyticus subsp. pasteurianus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus Pigment:  neg
    Health:   Negative
    Source:  human faeces, clinical sources (pharynx, blood, urine - CCUG) and tooth surfaces
    NaCl >6%:  6.5(neg)
    		Aesculin:  + Urea:  neg Starch:  neg Arginine:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Glucose:  + Ribose:  neg D-Tagatose:  d(neg) Lactose:  + Maltose:  + Melezitose:  d Melibiose:  d(neg) Sucrose:  + Trehalose:  + Glycogen:  neg Inulin:  neg Starch:  neg D-Arabitol:  neg Mannitol:  neg Sorbitol:  neg Me-α-D-Glc:  + NAc-α-GA:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  + Hippurate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Galactosidase:  d(+) β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + β-Mannosidase:  + ArgDH:  neg AlaPheProAA:  + GlyTrpAA:  neg LeuAA:  + PyrrolidAA:  neg AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  + Indole:  neg Pigment:  neg

    References

    SPECIFIC REFERENCES FOR STREPTOCOCCUS PASTEURIANUS
  • Poyart2002 - Taxonomic dissection of the Streptococcus bovis group by analysis of manganese-dependent superoxide dismutase gene (sodA) sequences: reclassification of 'Streptococcus infantarius subsp. coli' as Streptococcus lutetiensis sp. nov. and of Streptococcus bovis biotype II.2 as Streptococcus pasteurianus sp. nov.
  • Whiley2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Streptococcaceae, Genus I. Streptococcus
  • Bojovic2020 - Gut Microbiota Dysbiosis Associated With Altered Production of Short Chain Fatty Acids in Children With Neurodevelopmental Disorders
  • Kinumaki2015 - Characterization of the gut microbiota of Kawasaki disease patients by metagenomic analysis
  • Beck2008 - Comprehensive Study of Strains Previously Designated Streptococcus bovis Consecutively Isolated from Human Blood Cultures and Emended Description of Streptococcus gallolyticus and Streptococcus infantarius subsp. coli.
  • Schlegel2003 - Reappraisal of the taxonomy of the Streptococcus bovis/Streptococcus equinus complex and related species: description of Streptococcus gallolyticus subsp. gallolyticus subsp. nov., S. gallolyticus subsp. macedonicus subsp. nov. and S. gallolyticus subsp. pasteurianus subsp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR STREPTOCOCCUS PASTEURIANUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • King2019 - Baseline human gut microbiota profile in healthy people and standard reporting template.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • ...............................
    • GENERAL REFERENCES FOR STREPTOCOCCUS PASTEURIANUS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
  • Vos2011Bergey - Bergey's manual of systematic bacteriology: Vol. 3. The Firmicutes
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: March 29, 2021