Streptococcus timonensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Streptococcus timonensis is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 38.6%. Streptococcus timonensis is probably a common, although minor, coloniser of the gut. (Ricaboni2016g)



  • This organism has been recovered from stomach samples, France. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 16% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Ricaboni2016g);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 5; tolerates pH 8.0;
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; maltose; sucrose;
  • Active enzymes:
  • esterase C4; Leu arylamidase; leucine aminopeptidase;
    • SPECIAL FEATURES (Ricaboni2016g);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • Haemolysis:
  • alpha
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Ricaboni2016g);
    Class Active Resistant
  • Penicillins:
  • imipenem; penicillin G;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Streptococcaceae Genus:  Streptococcus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  stomach samples, France
    DNA G+C(%):  38.6
    Opt. T:  37℃
    Lower T(℃):  20(+)
    High T(℃):  45(neg)
    NaCl 3-5%:  5(neg)
    pH 4.2-5.9:  5(+)
    pH 6.0-8.0:  8.0(+)
    		Aesculin:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  + Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  neg Turanose:  neg Amygdalin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Starch:  w Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg LeuAP:  + Trypsin:  neg LeuAA:  + PyrrolidAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  neg Esterase(C4):  + EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  S(10U)
    imipenem:  S(10; disc)
    erythromycin:  Var(MIC50): 15U), MIC90: Var(15U
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(30; disc)
    rifampicin:  S(30; disc)
    SXT:  R(25; disc)

    References

    SPECIFIC REFERENCES FOR STREPTOCOCCUS TIMONENSIS
  • Ricaboni2016g - Noncontiguous finished genome sequence and description of Streptococcus timonensis sp. nov. isolated from the human stomach.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR STREPTOCOCCUS TIMONENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022