Streptococcus vestibularis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Streptococcus vestibularis is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 15 gut microbiome compilation studies or metastudies. The DNA G+C content is 38-40%. Streptococcus vestibularis is a common gut coloniser. (Whiley1988; Whiley2011Bergey)



  • This organism has been recovered from oral cavity, clinical sources (blood, ear - CCUG) and human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Is a rare opportunistic pathogen. A possible gut commensal. Robust growth can have unknown consequences for gut health.
    • QUIRKS
  • Found in human breast milk (Jeurink2013).
    • GENERAL CHARACTERISTICS (Whiley1988); (Whiley2011Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; starch; urea;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 4% salt;
  • 💧
  • Bile tolerance:
  • Resistant to 10% bile
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 10℃; doesn't grow at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; amygdalin; cellubiose; gentiobiose; lactose; maltose; sucrose; trehalose; α-methyl glucoside; salicin;
  • Active enzymes:
  • Ala arylamidase; Ala-Phe-Pro arylamidase; β-galactosidase; Leu arylamidase; urease;
  • ±
  • Strain-dependent active enzymes:
  • α-glucosidase;
    • SPECIAL FEATURES (Whiley1988); (Whiley2011Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • VP test:
  • active
  • Haemolysis:
  • alpha
  • ✗
  • Nitrate:
  • not reduced

  • Streptococci are members of the normal flora. Virulence factors of group A streptococci include (1) M protein and lipoteichoic acid for attachment; (2) a hyaluronic acid capsule that inhibits phagocytosis; (3) other extracellular products, such as pyrogenic (erythrogenic) toxin, which causes the rash of scarlet fever; and (4) streptokinase, streptodornase (DNase B), and streptolysins. Some strains are nephritogenic. Immune-mediated sequelae do not reflect dissemination of bacteria. Nongroup A strains have no defined virulence factors. In humans, diseases associated with the streptococci occur chiefly in the respiratory tract, bloodstream, or as skin infections. [https://www.ncbi.nlm.nih.gov/books/NBK7611/]

  • GutFeeling KnowledgeBase COMMENTS [Website]

    The genus Streptococcus , a heterogeneous group of Gram-positive bacteria, has broad significance in medicine and industry. Various streptococci are important ecologically as part of the normal microbial flora of animals and humans; some can also cause diseases that range from subacute to acute or even chronic. Among the significant human diseases attributable to streptococci are scarlet fever, rheumatic heart disease, glomerulonephritis, and pneumococcal pneumonia. Streptococci are essential in industrial and dairy processes and as indicators of pollution. [https://www.ncbi.nlm.nih.gov/books/NBK7611/]

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Streptococcaceae Genus:  Streptococcus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  oral cavity, clinical sources (blood, ear - CCUG) and human faeces
    DNA G+C(%):  38-40
    Low T(℃):  10(neg)
    High T(℃):  45(neg)
    NaCl 3-5%:  4(neg)
    Bile reaction(%):  10(+)
    		Aesculin:  + Urea:  + Starch:  + Arginine:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  d(+) Turanose:  neg Amygdalin:  + Dextrin:  neg Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  vr Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  d(+) Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  vr Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  neg Hippurate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  + Hyaluridonase:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  d β-Glucosidase:  vr β-Glucuronidase:  neg α-Mannosidase:  neg β-Mannosidase:  neg ArgDH:  neg GluDC:  neg AlanineAA:  + AlaPheProAA:  + GluGluAA:  neg GlyAA:  vr LeuAA:  + LeuGlyAA:  neg PyrrolidAA:  neg PyrogluAA:  neg AlkalineP:  neg AcidP:  neg Esterase(C4):  neg EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR STREPTOCOCCUS VESTIBULARIS
  • Whiley1988 - Streptococcus vestibularis sp. nov. from the Human Oral Cavity.
  • Whiley2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Streptococcaceae, Genus I. Streptococcus
  • Maji2018 - Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers
  • Qin2014 - Alterations of the human gut microbiome in liver cirrhosis
  • Zhou2018 - Alterations in the gut microbiota of patients with acquired immune deficiency syndrome
  • Zhu2020 - Metagenome-wide association of gut microbiome features for schizophrenia
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR STREPTOCOCCUS VESTIBULARIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Karlsson2013 - Gut metagenome in European women with normal, impaired and diabetic glucose control
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Pandey2012 - Comparative analysis of fecal microflora of healthy full-term Indian infants born with different methods of delivery (vaginal vs cesarean): Acinetobacter sp. prevalence in vaginally born infants.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • GENERAL REFERENCES FOR STREPTOCOCCUS VESTIBULARIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021