Subdoligranulum formicile

(aka Gemmiger formicilis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Subdoligranulum formicile, (aka Gemmiger formicilis), is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. Subdoligranulum formicile is probably a rare gut coloniser. (Gossling1975)



  • This organism has been recovered from human faeces (Gossling1975). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Gossling1975);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
    • SPECIAL FEATURES (Gossling1975);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (minor); butyrate; lactate; succinate (minor);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrite:
  • not reduced
  • NOTES

    Formerly known as Gemmiger formicilis. This is a common inhabitant of the human gut.

    Fuel sources used:
    It can use fibre, starch and simple sugars for energy.

    Metabolites produced:
    Our genomic analysis indicates that most members of this species can produce the following metabolites: acetate, B-glucuronidase, BCAAs, butyrate, lactate, cobalamin.

    Metabolites consumed:
    In addition, our genomic analysis indicates that most members of this species can consume the following metabolites: oxalate.

  • References: [1] [2] [3]

  • Holmstrøm, K., Collins, M. D., Møller, T., Falsen, E., & Lawson, P. A. (2004). Subdoligranulum variabile gen. nov., sp. nov. from human feces. Anaerobe, 10(3), 197–203.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Oscillospiraceae Genus:  Subdoligranulum Alt. name:  Gemmiger formicilis Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  human faeces (Gossling1975)
    		Aesculin:  + Starch:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  minor(+) Butyrate:  + Lactate:  + Succinate:  minor(+) Indole:  neg

    References

    SPECIFIC REFERENCES FOR SUBDOLIGRANULUM FORMICILE
  • Gossling1975 - Gemmiger formicilis, n.gen., n.sp., an Anaerobic Budding Bacterium from Intestines.
  • Dong2020a - The Association of Gut Microbiota With Idiopathic Central Precocious Puberty in Girls
  • Huang2019 - Analysis of microbiota in elderly patients with Acute Cerebral Infarction
  • KowalskaDuplaga2019 - Differences in the intestinal microbiome of healthy children and patients with newly diagnosed Crohn's disease
  • Malham2019 - The microbiome reflects diagnosis and predicts disease severity in paediatric onset inflammatory bowel disease
  • ...............................
    • GENERAL REFERENCES FOR SUBDOLIGRANULUM FORMICILE
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: February 08, 2021