Sutterella megalosphaeroides

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Sutterella megalosphaeroides is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 62.8%. Sutterella megalosphaeroides is probably a rare gut coloniser. (Sakamoto2018b)



  • This organism has been recovered from human faeces (Sakamoto2018b). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Sakamoto2018b);
    Character Response
  • 💧
  • Bile tolerance:
  • Grows weakly in 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 20℃; grows at 45℃; Grows optimally at 37℃.
  • Active enzymes:
  • Arg arylamidase;
    • SPECIAL FEATURES (Sakamoto2018b);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Sakamoto2018b);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; penicillin G;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • oxytetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin; kanamycin; neomycin;
  • streptomycin;
  • Polypep/ketides:
  • bacitracin;
  • Heterocycles:
  • chloramphenicol;
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Burkholderiales Family:  Sutterellaceae Genus:  Sutterella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus Pigment:  neg
    Health:  Unknown
    Source:  human faeces (Sakamoto2018b)
    DNA G+C(%):  62.8
    Opt. T:  37℃
    Lower T(℃):  20(+)
    High T(℃):  45(+)
    Bile reaction(%):  20(w)
    		Aesculin:  neg Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  neg Mannose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg G6PDH6PGDH:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  w ArgAA:  + CystineAA:  neg GluGluAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  w LeuGlyAA:  neg ProAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  neg Esterase(C4):  w EstLip(C8):  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  R(25; disc)
    penicillin_G:  R(10U)
    gentamicin:  S(10; disc)
    kanamycin:  S(30; disc)
    neomycin:  S(30; disc)
    streptomycin:  R(10)
    erythromycin:  S(15; disc)
    ciprofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    oxytetracycline:  S(30; disc)
    vancomycin:  R(30; disc)
    bacitracin:  S(10U)
    chloramphenicol:  S(30; disc)
    SXT:  R(25; disc)
    colistin:  S(10; disc)

    References

    SPECIFIC REFERENCES FOR SUTTERELLA MEGALOSPHAEROIDES
  • Sakamoto2018b - Mesosutterella multiformis gen. nov., sp. nov., a member of the family Sutterellaceae and Sutterella megalosphaeroides sp. nov., isolated from human faeces.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR SUTTERELLA MEGALOSPHAEROIDES
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: July 12, 2021