Tannerella serpentiformis

(aka Tannerella sp. HOT-286)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Tannerella serpentiformis, (aka Tannerella sp. HOT-286), is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, filamentous bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 56.5%. Tannerella serpentiformis is likely to be transient and not a long-term gut coloniser. (Ansbro2020; Vartoukian2016)



  • This organism has been recovered from the human mouth. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Ansbro2020); (Vartoukian2016);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows at 37℃;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; Arg arylamidase; α-glucosidase; His arylamidase; Leu arylamidase; Leu-Gly arylamidase; Phe arylamidase; pyroGlu arylamidase; trypsin; Tyr arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Ansbro2020); (Vartoukian2016);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Vartoukian2016);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; ampicillin;
  • Cephalosporins:
  • ceftazidime;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Heterocycles:
  • metronidazole;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Tannerellaceae Genus:  Tannerella Alt. name:  Tannerella sp. HOT-286 Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Filamentous
    Health:  Unknown
    Source:  the human mouth
    DNA G+C(%):  56.5
    Mid T(℃):  37(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Mannose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg GluDC:  neg Trypsin:  + AlanineAA:  + ArgAA:  + CystineAA:  neg GluGluAA:  neg HisAA:  + LeuAA:  + LeuGlyAA:  + ProAA:  neg PheAA:  + PyrogluAA:  + SerAA:  neg TyrAA:  + ValAA:  neg AlkalineP:  + AcidP:  vr Esterase(C4):  neg EstLip(C8):  w Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(10; disc)
    ampicillin:  S(2; disc)
    penicillin:  Var(MIC50): 1U), MIC90: Var(1U
    ceftazidime:  S(30; disc)
    gentamicin:  R(10; disc)
    erythromycin:  S(5; disc)
    ciprofloxacin:  R(1; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(10; disc)
    chloramphenicol:  Var(MIC50): 10; disc), MIC90: Var(10; disc
    metronidazole:  S(5; disc)

    References

    SPECIFIC REFERENCES FOR TANNERELLA SERPENTIFORMIS
  • Ansbro2020 - Tannerella serpentiformis sp. nov., isolated from the human mouth.
  • Vartoukian2016 - First Cultivation of Health-Associated Tannerella sp. HOT-286 (BU063).
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR TANNERELLA SERPENTIFORMIS
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022