Terrisporobacter mayombei

(aka Clostridium mayombei)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Terrisporobacter mayombei, (aka Clostridium mayombei), is a Gram-positive, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 25.6%. Terrisporobacter mayombei is probably a rare gut coloniser. (Gerritsen2014; Kane1991)



  • This organism has been recovered from human faeces and termite gut. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Gerritsen2014); (Kane1991);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 5.5; tolerates pH 9.3; Grows optimally at pH 7.3.
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 45℃; Grows optimally at 33℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; xylose; dextrin; aesculin; starch; cellubiose; maltose; pyruvate; dulcitol; glycerol; sorbitol; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • cellubiose; dextrin; dulcitol; aesculin; fructose; glucose; glycerol; maltose; salicin; sorbitol; starch; xylose; alanine; glutamate; serine; valine; formate; malate; pyruvate; glutamine;
    • SPECIAL FEATURES (Gerritsen2014); (Kane1991);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate; isobutyrate; CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • H₂S;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Sulfate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Cheng2016);
    Class Active Resistant
  • Penicillins:
  • meropenem; penicillin; piperacillin-tazobactam;
  • imipenem;
  • Cephalosporins:
  • cefoxitin;
  • Quinolines:
  • moxifloxacin;
  • Heterocycles:
  • metronidazole;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Peptostreptococcaceae Genus:  Terrisporobacter Alt. name:  Clostridium mayombei Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and termite gut
    DNA G+C(%):  25.6
    Opt. T:  33℃
    Low T(℃):  15(+)
    High T(℃):  45(+)
    Opt. pH:  7.3
    pH 4.2-5.9:  5.5(+)
    pH >8:  9.3(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  + Glucose:  + Xylose:  + Cellubiose:  + Maltose:  + Dextrin:  + Aesculin:  + Starch:  + Dulcitol:  + Glycerol:  + Sorbitol:  + Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Fucose:  neg Galactose:  neg Glucose:  + Mannose:  neg Rhamnose:  neg Ribose:  neg Xylose:  + Cellubiose:  + Lactose:  neg Maltose:  + Melibiose:  neg Raffinose:  neg Sucrose:  neg Trehalose:  neg Adonitol:  neg Dextrin:  + Dulcitol:  + Erythritol:  neg Aesculin:  + Ethanol:  neg Gluconate:  neg Glycerol:  + Mannitol:  neg Methanol:  neg Pectin:  neg Propanol:  neg Salicin:  + Sorbitol:  + Starch:  + Ala:  + Betaine:  neg Glu:  + Ser:  + Val:  + Acetate:  neg Benzoate:  neg Citrate:  neg Formate:  + Fumarate:  neg 3-Hydroxybenzoate:  neg Lactate:  neg Malate:  + Pyruvate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  + Isobutyrate:  + H2S:  neg CO2:  + H2:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  S(1)
    piper-taz:  S(1.5)
    imipenem:  R(32)
    meropenem:  S(1)
    cefoxitin:  R(32)
    moxifloxacin:  S(1)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    metronidazole:  S(0.5)
    clindamycin:  S(0.125)

    References

    SPECIFIC REFERENCES FOR TERRISPOROBACTER MAYOMBEI
  • Gerritsen2014 - Characterization of Romboutsia ilealis gen. nov., sp. nov., isolated from the gastro-intestinal tract of a rat, and proposal for the reclassification of five closely related members of the genus Clostridium into the genera Romboutsia gen. nov., Intestinibacter gen. nov., Terrisporobacter gen. nov. and Asaccharospora gen. nov.
  • Cheng2016 - A case report of a deep surgical site infection with Terrisporobacter glycolicus/T. Mayombei and review of the literature.
  • Kane1991 - Clostridium mayombei sp. nov., an H2/C02 acetogenic bacterium from the gut of the African soil-feeding termite, Cubitermes speciosus
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR TERRISPOROBACTER MAYOMBEI
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
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    • Added: December 15, 2021