Thermolithobacter ferrireducens

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Thermolithobacter ferrireducens is a Gram-positive, non-spore-forming, strictly anaerobic, motile, short rod-shaped bacterium. The DNA G+C content is 52-53%. Thermolithobacter ferrireducens is unlikely to be a gut coloniser. (Sokolova2007)



  • This organism has been recovered from hot spring outflow, Yellowstone National Park, USA. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Reduces Fe(III). Non-coloniser due to very high minimum growth temperature.
    • GENERAL CHARACTERISTICS (Sokolova2007);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 6.5; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 50-73℃; Grows optimally at 73℃.
  • ⥅
  • Substrates assimilated or utilised:
  • fumarate; Casamino acids; H2 consumed; CO2 consumed;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Sulfate:
  • not reduced
  • ✓
  • Thiosulfate:
  • reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • ampicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Aminoglycosides:
  • streptomycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Thermolithobacteria Order:  Thermolithobacterales Family:  Thermolithobacteraceae Genus:  Thermolithobacter Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Short Rod
    Health:  Unknown
    Source:  hot spring outflow, Yellowstone National Park, USA
    DNA G+C(%):  52-53
    Opt. T:  73℃
    High T(℃):  50-73(+)
    pH 6.0-8.0:  6.5(+)
    pH >8:  8.5(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Citrate:  neg Fumarate:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  R(100; disc)
    streptomycin:  R(10; disc)
    erythromycin:  R(10; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  R(100; disc)
    rifampicin:  R(10; disc)
    chloramphenicol:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR THERMOLITHOBACTER FERRIREDUCENS
  • Scanlan2012 - Gut dysbiosis in cystic fibrosis
  • Sokolova2007 - Novel chemolithotrophic, thermophilic, anaerobic bacteria Thermolithobacter ferrireducens gen. nov., sp. nov. and Thermolithobacter carboxydivorans sp. nov.
  • ...............................
    • Added: September 19, 2022