Treponema phagedenis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Treponema phagedenis is a Gram-negative, non-spore-forming, strictly anaerobic, motile, spirochete bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 39.9-40.1%. Treponema phagedenis is likely to be transient and not a long-term gut coloniser. (Kuhnert2020)



  • This organism has been recovered from bovine digital dermatitis legions. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Kuhnert2020);
    Character Response
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; esterase C4; fucosidase; β-galactosidase; Leu arylamidase; naphthol-ASBI-P;
  • ±
  • Strain-dependent active enzymes:
  • β-glucuronidase; pyrrolidine arylamidase;
    • SPECIAL FEATURES (Kuhnert2020);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Spirochaetes Class:  Spirochaetia Order:  Spirochaetales Family:  Treponemataceae Genus:  Treponema Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Spirochete
    Health:  Unknown
    Source:  bovine digital dermatitis legions
    DNA G+C(%):  39.9-40.1
    Opt. T:  37℃
    		Aesculin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Galactose:  neg Glucose:  neg Mannose:  neg Ribose:  neg Xylose:  neg Cellubiose:  neg Maltose:  neg Maltotriose:  neg Sucrose:  neg N_Acetyl_glucosamine:  neg Arbutin:  neg Pyruvate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Arab:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  d α-Mannosidase:  neg β-Mannosidase:  neg Chymotrypsin:  neg Trypsin:  neg AlaPheProAA:  neg CystineAA:  neg LeuAA:  d(+) ProAA:  neg PyrrolidAA:  d(neg) ValAA:  neg AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +

    References

    SPECIFIC REFERENCES FOR TREPONEMA PHAGEDENIS
  • Kuhnert2020 - Treponema phagedenis (ex Noguchi 1912) Brumpt 1922 sp. nov., nom. rev., isolated from bovine digital dermatitis.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR TREPONEMA PHAGEDENIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022