Turicibacter sanguinis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Turicibacter sanguinis is a Gram-positive, non-spore-forming, strictly anaerobic, rod-shaped bacterium. It has been detected in at least 20 gut microbiome compilation studies or metastudies. The DNA G+C content is 36.9%. Turicibacter sanguinis is a common gut coloniser. (Bosshard2002; Bosshard2011Bergey)



  • This organism has been recovered from clinical sources (abscess, blood, appendix - CCUG) and human faeces (gut). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). It is an opportunistic pathogen. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Bosshard2002); (Bosshard2011Bergey);
    Character Response
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7.5.
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 46℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • maltose; 5-ketogluconate;
  • ⥅
  • Substrates assimilated or utilised:
  • maltose; 5-ketogluconate;
  • Active enzymes:
  • alkaline phosphatase; N-Ac β-glucosaminidase; α-galactosidase; β-galactosidase; α-glucosidase; pyrrolidine arylamidase;
    • SPECIAL FEATURES (Bosshard2002); (Bosshard2011Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (minor); lactate;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Bosshard2002); (Bosshard2011Bergey);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Aminoglycosides:
  • kanamycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

  • Cuív, P. Ó., Klaassens, E. S., Durkin, A. S., Harkins, D. M., Foster, L., McCorrison, J., Torralba, M., Nelson, K. E., & Morrison, M. (2011). Draft genome sequence of Turicibacter sanguinis PC909, isolated from human feces. Journal of Bacteriology, 193(5), 1288–1289.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Erysipelotrichia Order:  Erysipelotrichales Family:  Erysipelotrichaceae Genus:  Turicibacter Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Morphology:  Rod
    Health:   Positive
    Source:  clinical sources (abscess, blood, appendix - CCUG) and human faeces (gut)
    DNA G+C(%):  36.9
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  46(+)
    Opt. pH:  7.5
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Maltose:  + 5-Ketogluconate:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Maltose:  + 5-Ketogluconate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  neg β-Glucuronidase:  neg ArgDH:  neg GluDC:  neg AlanineAA:  neg GluGluAA:  neg GlyAA:  neg LeuAA:  neg LeuGlyAA:  neg PyrrolidAA:  + AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  minor(+) Lactate:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  Sens
    kanamycin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR TURICIBACTER SANGUINIS
  • Bosshard2002 - Turicibacter sanguinis gen. nov., sp. nov., a novel anaerobic, Gram-positive bacterium.
  • Bosshard2011Bergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Erysipelotrichaceae, Genus VIII. Turicibacter
  • DeAngelis2013 - Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified
  • Malham2019 - The microbiome reflects diagnosis and predicts disease severity in paediatric onset inflammatory bowel disease
  • MorenoArrones2019 - Analysis of the gut microbiota in alopecia areata: identification of bacterial biomarkers
  • Luna2016 - Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR TURICIBACTER SANGUINIS
  • Browne2016 - Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation.
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • McLaughlin2010 - The bacteriology of pouchitis: a molecular phylogenetic analysis using 16S rRNA gene cloning and sequencing.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Pfleiderer2013 - Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • GENERAL REFERENCES FOR TURICIBACTER SANGUINIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021