Yersinia pseudotuberculosis

(aka Pasteurella lymphangitidis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Yersinia pseudotuberculosis, (aka Pasteurella lymphangitidis), is a Gram-negative, non-spore-forming, facultatively anaerobic, variably-motile, coccobacillus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 46.5%. Yersinia pseudotuberculosis is likely to be transient and not a long-term gut coloniser. (Farmer1985; Gaillot2013; Bottone2005Bergey; Sneath1990)



  • This organism has been recovered from clinical sources (blood, lymph node - CCUG) and human faeces. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: zoonotic pathogen). Could be a possible pathogen in humans, but unknown at this stage. Likely to be transient and not a long-term gut commensal. Robust growth can have negative consequences for gut health.
    • GENERAL CHARACTERISTICS (Farmer1985); (Gaillot2013); (Bottone2005Bergey); (Sneath1990);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; urea;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 28-29℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; galactose; glucose; mannose; rhamnose; ribose; xylose; melibiose; trehalose; glycerol; mannitol; arbutin; β-methyl glucoside;
  • ±
  • Strain-dependent acid from carbs:
  • maltose; sucrose; salicin;
  • Active enzymes:
  • Ala-Phe-Pro arylamidase; alkaline phosphatase; acid phosphatase; catalase; esterase C4; γ-Glu transferase; β-glucosidase; Leu arylamidase; pyrrolidine arylamidase; urease;
    • SPECIAL FEATURES (Farmer1985); (Bottone2005Bergey); (Sneath1990);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • ONPG test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • Nitrate:
  • reduction is variable
  • ✓
  • NO3➔NO2:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Bottone2005Bergey);
    Class Active Resistant
  • Penicillins:
  • aztreonam; imipenem;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Aminoglycosides:
  • amikacin; gentamicin; kanamycin; neomycin; streptomycin;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • novobiocin;

  • Chiesa, C., Pacifico, L., Nanni, F., Renzi, A. M., & Ravagnan, G. (1993). Yersinia pseudotubetculosisin Italy. Attempted Recovery from 37,666 Samples. Microbiology and Immunology, 37(5), 391–394.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Enterobacterales Family:  Yersiniaceae Genus:  Yersinia Alt. name:  Pasteurella lymphangitidis Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  vr Morphology:  Coccobacillus
    Health:   Negative
    Source:  clinical sources (blood, lymph node - CCUG) and human faeces
    DNA G+C(%):  46.5
    Opt. T:  28-29℃
    		Aesculin:  + Urea:  + Gelatin:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg L-Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Ribose:  + Sorbose:  neg D-Tagatose:  neg Xylose:  + Cellubiose:  neg Lactose:  neg Maltose:  d Melezitose:  neg Melibiose:  + Sucrose:  d Trehalose:  + Dextrin:  neg Glycogen:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  vr Dulcitol:  neg Glycerol:  + Inositol:  neg Mannitol:  + Sorbitol:  neg Arbutin:  + 5-Ketogluconate:  neg Me-α-D-Glc:  neg Salicin:  d
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Citrate:  neg Mucate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  + Ac-β-glcamnd:  neg α-Fucosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg β-Mannosidase:  neg ArgDH:  neg γ-Glu transf.:  + LysDC:  neg OrnDC:  neg AlaPheProAA:  + LeuAA:  + PyrrolidAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  neg Lipase:  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Var
    aztreonam:  Sens
    penicillin:  Var
    imipenem:  Sens
    amikacin:  Sens
    gentamicin:  Sens
    kanamycin:  Sens
    neomycin:  Sens
    streptomycin:  Sens
    erythromycin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Sens
    chloramphenicol:  Sens
    novobiocin:  Res
    colistin:  Var

    References

    SPECIFIC REFERENCES FOR YERSINIA PSEUDOTUBERCULOSIS
  • Farmer1985 - Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens.
  • Gaillot2013 - Proposed reclassification of Pasteurella lymphangitidis Sneath and Stevens 1990 as Yersinia pseudotuberculosis.
  • Bottone2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Gammaproteobacteria Part B. Family Enterobacteriaceae, Genus XLI. Yersinia
  • Sneath1990 - Actinobacillus rossii sp. nov., Actinobacillus seminis sp. nov., nom. rev., Pasteurella bettii sp. nov., Pasteurella lymphangitidis sp. nov., Pasteurella mairi sp. nov., and Pasteurella trehalosi sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR YERSINIA PSEUDOTUBERCULOSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR YERSINIA PSEUDOTUBERCULOSIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021