HMO - Hexaose Core

Table 1. A summary of the compounds based on the lacto-N-hexaose (LNH) core.

Figure Section Name LNH Type Configuration Abbreviation
  Non-sialylated Hexaose Cores        
1 Unsubstituted LNHs Lacto-N-neohexaose   neo- LNnH
2 Unsubstituted LNHs para-Lacto-N-neohexaose   neo-, para-
 para-LNnH
3 Unsubstituted LNHs Lacto-N-hexaose     LNH
4 Unsubstituted LNHs para-Lacto-N-hexaose   para- para-LNH
5 Difucohexaose Lacto-N-difucohexaose I Difuco   LNDFH I
6 Difucohexaose Lacto-N-difucohexaose II Difuco   LNDFH II
7 Difucohexaose Lacto-N-difucohexaose III Difuco   LNDFH III
8 Monofucosyl para-hexaoses Fucosyl-para-lacto-N-hexaose I Monofucosyl para- F-para-LNH I
9 Monofucosyl para-hexaoses Fucosyl-para-lacto-N-hexaose II Monofucosyl para- F-para-LNH II
10 Monofucosyl para-hexaoses Fucosyl-para-lacto-N-neohexaose Monofucosyl neo-, para-
 F-para-LNnH
11 Difucosyl para-hexaoses Difucosyl-para-lacto-N-hexaose Difucosyl para- DF-para-LNH
12 Difucosyl para-hexaoses Difucosyl-para-lacto-N-hexaose II Difucosyl para- DF-para-LNH II
13 Difucosyl para-hexaoses Difucosyl-para-lacto-N-hexaose III Difucosyl para- DF-para-LNH III
14 Difucosyl para-hexaoses Difucosyl-para-lacto-N-neohexaose Difucosyl neo-, para- DF-para-LNnH
15 Trifucosyl para-hexaoses Trifucosyl-para-lacto-N-hexaose I Trifucosyl para- TF-para-LNH I
16 Trifucosyl para-hexaoses Trifucosyl-para-lacto-N-hexaose II Trifucosyl para- TF-para-LNH II
17 Trifucosyl para-hexaoses Trifucosyl-para-lacto-N-neohexaose Trifucosyl neo-, para- TF-para-LNnH
18 Monofucosyl hexaoses Fucosyllacto-N-hexaose I Monofucosyl   F-LNH I
19 Monofucosyl hexaoses Fucosyllacto-N-hexaose II Monofucosyl   F-LNH II
20 Monofucosyl hexaoses Fucosyllacto-N-hexaose III Monofucosyl   F-LNH III
21 Monofucosyl hexaoses Fucosyllacto-N-neohexaose I Monofucosyl neo- F-LNnH I
22 Monofucosyl hexaoses Fucosyllacto-N-neohexaose II Monofucosyl neo- F-LNnH II
23 Difucosyl hexaoses Difucosyllacto-N-hexaose I Difucosyl   DF-LNH I
24 Difucosyl hexaoses Difucosyllacto-N-hexaose II Difucosyl   DF-LNH II
25 Difucosyl hexaoses Difucosyllacto-N-neohexaose Difucosyl neo- DF-LNnH
26 Trifucosyl hexaoses Trifucosyllacto-N-hexaose I Trifucosyl   TF-LNH I
27 Trifucosyl hexaoses Trifucosyllacto-N-hexaose II Trifucosyl   TF-LNH II
  Sialylated Hexaose Cores        
28 Monosialyl Hexaoses Sialyllacto-N-hexaose I Monosialyl   S-LNH I
29 Monosialyl Hexaoses Sialyllacto-N-hexaose II Monosialyl   S-LNH II
30 Monosialyl Hexaoses Sialyllacto-N-neohexaose I Monosialyl neo- S-LNnH I
31 Monosialyl Hexaoses Sialyllacto-N-neohexaose II Monosialyl neo- S-LNnH II
32 Monosialyl Hexaoses Sialyl-para-lacto-N-neohexaose Monosialyl neo-, para- S-para-LNnH
33 Monosialylated Monofucosylated Hexaoses Fucosylsialyllacto-N-hexaose Monofucosyl monosialyl   FS-LNH
34 Monosialylated Monofucosylated Hexaoses Fucosylsialyllacto-N-hexaose I Monofucosyl monosialyl   FS-LNH I
35 Monosialylated Monofucosylated Hexaoses Fucosylsialyllacto-N-hexaose II Monofucosyl monosialyl   FS-LNH II
36 Monosialylated Monofucosylated Hexaoses Fucosylsialyllacto-N-hexaose III Monofucosyl monosialyl   FS-LNH III
37 Monosialylated Monofucosylated Hexaoses Fucosylsialyllacto-N-hexaose IV Monofucosyl monosialyl   FS-LNH IV
38 Monosialylated Monofucosylated Hexaoses Fucosylsialyllacto-N-neohexaose I Monofucosyl monosialyl neo- FS-LNnH I
39 Monosialylated Monofucosylated Hexaoses Fucosylsialyllacto-N-neohexaose II Monofucosyl monosialyl neo- FS-LNnH II
40 Monosialylated Monofucosylated Hexaoses Fucosylsialyl-para-lacto-N-neohexaose I Monofucosyl monosialyl neo-, para- FS-para-LNnH I
41 Monosialylated Monofucosylated Hexaoses Fucosylsialyl-para-lacto-N-neohexaose II Monofucosyl monosialyl neo-, para- FS-para-LNnH II
42 Monosialylated Difucosylated Hexaoses Difucosylsialyllacto-N-hexaose Kitagawa1989 Difucosyl monosialyl    
43 Monosialylated Difucosylated Hexaoses Difucosylsialyllacto-N-hexaose I Difucosyl monosialyl   DFS-LNH I
44 Monosialylated Difucosylated Hexaoses Difucosylsialyllacto-N-hexaose III Difucosyl monosialyl   DFS-LNH III
45 Monosialylated Difucosylated Hexaoses Difucosylsialyllacto-N-hexaose IV Difucosyl monosialyl   DFS-LNH IV
46 Monosialylated Difucosylated Hexaoses Difucosylsialyllacto-N-neohexaose Difucosyl monosialyl neo- DFS-LNnH
47 Monosialylated Difucosylated Hexaoses Difucosylsialyl-para-lacto-N-hexaose I Difucosyl monosialyl para-  
48 Monosialylated Difucosylated Hexaoses Difucosylsialyl-para-lacto-N-hexaose II Difucosyl monosialyl para-  
49 Monosialylated Trifucosylated Hexaoses Sialyltrifucosyl-para-lacto-N-hexaose Trifucosyl monosialyl para-  
50 Disialylated Hexaoses Disialyllacto-N-hexaose I Disialyl   DS-LNH I
51 Disialylated Hexaoses Disialyllacto-N-hexaose II Disialyl   DS-LNH II
52 Disialylated Hexaoses Disialyllacto-N-neohexaose Disialyl neo- DS-LNnH
53 Disialylated Monofucosylated Hexaoses Disialylfucosyllacto-N-hexaose Yamashita1976 Disialyl Monofucosyl    
54 Disialylated Monofucosylated Hexaoses Disialylfucosyllacto-N-hexaose I or Fucosyldisialyllacto-N-hexaose I Disialyl Monofucosyl   FDS-LNH I

55

 Disialylated Monofucosylated Hexaoses Disialylfucosyllacto-N-hexaose II or Fucosyldisialyllacto-N-hexaose II Disialyl Monofucosyl   FDS-LNH II
56 Disialylated Monofucosylated Hexaoses Disialylfucosyllacto-N-hexaose III or Fucosyldisialyllacto-N-hexaose III Disialyl Monofucosyl   FDS-LNH III
57 Disialylated Monofucosylated Hexaoses Disialylfucosyllacto-N-neohexaose or Fucosyldisialyllacto-N-neohexaose Disialyl Monofucosyl neo- FDS-LNnH
58 Trisialylated Hexaoses Trisialyllacto-N-hexaose Trisialyl   TS-LNH

 

Non-sialylated hexaose Cores

Unsubstituted LNHs

Figure 1. Lacto-N-neohexaose (LNnH).

Figure 2. para-Lacto-N-neohexaose (para-LNnH).

Figure 3. Lacto-N-hexaose (LNH).

Figure 4. para-Lacto-N-hexaose (para-LNH).

 

Difucohexaose

Figure 5. Lacto-N-difucohexaose I (LNDFH I).

Figure 6. Lacto-N-difucohexaose II (LNDFH II).

Figure 7. Lacto-N-difucohexaose III (LNDFH III).

 

Monofucosyl para-hexaoses

Figure 8. Fucosyl-para-lacto-N-hexaose I (F-para-LNH I).

Figure 9. Fucosyl-para-lacto-N-hexaose II (F-para-LNH II).

Figure 10. Fucosyl-para-lacto-N-neohexaose (F-para-LNnH).

 

Difucosyl para-hexaoses

Figure 11. Difucosyl-para-lacto-N-hexaose (DF-para-LNH).

Figure 12. Difucosyl-para-lacto-N-hexaose II (DF-para-LNH II).

Figure 13. Difucosyl-para-lacto-N-hexaose III (DF-para-LNH III).

Figure 14. Difucosyl-para-lacto-N-neohexaose (DF-para-LNnH).

 

Trifucosyl para-hexaoses

Figure 15. Trifucosyl-para-lacto-N-hexaose I (TF-para-LNH I).

Figure 16. Trifucosyl-para-lacto-N-hexaose II (TF-para-LNH II).

Figure 17. Trifucosyl-para-lacto-N-neohexaose (TF-para-LNnH).

 

Monofucosyl hexaoses

Figure 18. 2'-Fucosyllacto-N-hexaose I (F-LNH I).

Figure 19. Fucosyllacto-N-hexaose II (F-LNH II).

Figure 20. Fucosyllacto-N-hexaose III (F-LNH III).

Figure 21. Fucosyllacto-N-neohexaose I (F-LNnH I).

Figure 22. Fucosyllacto-N-neohexaose II (F-LNnH II).

 

Difucosyl hexaoses

Figure 23. Difucosyllacto-N-hexaose I (DF-LNH I).

Figure 24. Difucosyllacto-N-hexaose II (DF-LNH II).

Figure 25. Difucosyllacto-N-neohexaose (DF-LNnH).

 

Trifucosyl hexaoses

Figure 26. Trifucosyllacto-N-hexaose I (TF-LNH I).

Figure 27. Trifucosyllacto-N-hexaose II (TF-LNH II).

 

Sialylated Hexaose Cores

Monosialyl Hexaoses

Figure 28. Sialyllacto-N-hexaose I (S-LNH I).

Figure 29. Sialyllacto-N-hexaose II (S-LNH II).

Figure 30. Sialyllacto-N-neohexaose I (S-LNnH I).

Figure 31. Sialyllacto-N-neohexaose II (S-LNnH II).

Figure 32. Sialyl-para-lacto-N-neohexaose (S-para-LNnH).

 

Monosialylated Monofucosylated Hexaoses

Figure 33. Fucosylsialyllacto-N-hexaose (FS-LNH).

Figure 34. Fucosylsialyllacto-N-hexaose I (FS-LNH I).

Figure 35. Fucosylsialyllacto-N-hexaose II (FS-LNH II).

Figure 36. Fucosylsialyllacto-N-hexaose III (FS-LNH III).

Figure 37. Fucosylsialyllacto-N-hexaose IV (FS-LNH IV).

Figure 38. Fucosylsialyllacto-N-neohexaose I (FS-LNnH I).

Figure 39. Fucosylsialyllacto-N-neohexaose II (FS-LNnH II).

Figure 40. Fucosylsialyl-para-lacto-N-neohexaose I (FS-para-LNnH I).

Figure 41. Fucosylsialyl-para-lacto-N-neohexaose II (FS-para-LNnH II).

 

Monosialylated Difucosylated Hexaoses

Figure 42. Difucosylsialyllacto-N-hexaose Kitagawa1989.

Figure 43. Difucosylsialyllacto-N-hexaose I (DFS-LNH I).

Figure 44. Difucosylsialyllacto-N-hexaose III (DFS-LNH III).

Figure 45. Difucosylsialyllacto-N-hexaose IV (DFS-LNH IV).

Figure 46. Difucosylsialyllacto-N-neohexaose (DFS-LNnH).

Figure 47. Difucosylsialyl-para-lacto-N-hexaose I.

Figure 48. Difucosylsialyl-para-lacto-N-hexaose II.

 

Monosialylated Trifucosylated Hexaoses

Figure 49. Sialyltrifucosyl-para-lacto-N-hexaose.

 

Disialylated Hexaoses

Figure 50. Disialyllacto-N-hexaose I (DS-LNH I).

Figure 51. Disialyllacto-N-hexaose II (DS-LNH II).

Figure 52. Disialyllacto-N-neohexaose (DS-LNnH).

 

Disialylated Monofucosylated Hexaoses

Figure 53. Disialylfucosyllacto-N-hexaose Yamashita1976.

Figure 54. Disialylfucosyllacto-N-hexaose I or Fucosyldisialyllacto-N-hexaose I (FDS-LNH I).

Figure 55. Disialylfucosyllacto-N-hexaose II or Fucosyldisialyllacto-N-hexaose II (FDS-LNH II).

Figure 56. Disialylfucosyllacto-N-hexaose III or Fucosyldisialyllacto-N-hexaose III (FDS-LNH III).

Figure 57. Disialylfucosyllacto-N-neohexaose or Fucosyldisialyllacto-N-neohexaose (FDS-LNnH).

 

Trisialylated Hexaoses

Figure 58. Trisialyllacto-N-hexaose (TS-LNH).