HMO - Tetraose & Tetrasaccharide Cores

Table 1. A summary of the compounds based around tetraose and tetrasaccharide cores.

Figure Section Name LND Type Configuration Abbreviation
  Non-sialylated        
1   Lacto-N-neotetraose   neo- LNnT
2   Lacto-N-tetraose     LNT
3   Lactodifucotetraose Difucosyl   LD
  Sialylated        
4   LS Tetrasaccharide a Monosialyl   LST a
5   LS Tetrasaccharide b Monosialyl   LST b
6   LS Tetrasaccharide c Monosialyl   LST c
7   LS Tetrasaccharide d Monofucosyl monosialyl   LST d
8   Fucosyl-LS Tetrasaccharide a Monofucosyl monosialyl   F-LST a
9   Fucosyl-LS Tetrasaccharide b Monofucosyl monosialyl   F-LST b
10   Fucosyl-LS Tetrasaccharide c Monofucosyl monosialyl   F-LST c
11   3-Fucosyl-sialyllacto-N-tetraose II Monofucosyl monosialyl   3-F LTS c
12   Disialyllacto-N-tetraose Disialyl   DS-LNT

 

Non-sialylated Tetraoses

Figure 1. Lacto-N-neotetraose (LNnT)

Figure 2. Lacto-N-tetraose (LNT)

Figure 3. Lactodifucotetraose (LD) or Difucosyllactose (DF-L)

 

Sialylated Tetraoses and Tetrasaccharides

Figure 4. LS Tetrasaccharide a (LST a).

Figure 5. LS Tetrasaccharide b (LST b).

Figure 6. LS Tetrasaccharide c (LST c).

Figure 7. LS Tetrasaccharide d (LST d).

Figure 8. Fucosyl-LS Tetrasaccharide a (F-LST a).

Figure 9. Fucosyl-LS Tetrasaccharide b (F-LST b).

Figure 10. Fucosyl-LS Tetrasaccharide c (F-LST c).

Figure 11. 3-Fucosyl-sialyllacto-N-tetraose II (3-F LTS c).

Figure 12. Disialyllacto-N-tetraose (DS-LNT)